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Design of a series of bicyclic HIV-1 integrase inhibitors. Part 1: selection of the scaffold.
Bioorg Med Chem Lett. 2010 Oct 1;20(19):5913-7. doi: 10.1016/j.bmcl.2010.07.079. Epub 2010 Jul 27.
Bioorg Med Chem Lett. 2010.
PMID: 20727748
Design of a series of bicyclic HIV-1 integrase inhibitors. Part 2: azoles: effective metal chelators.
Le G, Vandegraaff N, Rhodes DI, Jones ED, Coates JA, Thienthong N, Winfield LJ, Lu L, Li X, Yu C, Feng X, Deadman JJ.
Le G, et al. Among authors: winfield lj.
Bioorg Med Chem Lett. 2010 Oct 1;20(19):5909-12. doi: 10.1016/j.bmcl.2010.07.081. Epub 2010 Jul 27.
Bioorg Med Chem Lett. 2010.
PMID: 20727753
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Structural basis for a new mechanism of inhibition of HIV-1 integrase identified by fragment screening and structure-based design.
Rhodes DI, Peat TS, Vandegraaff N, Jeevarajah D, Le G, Jones ED, Smith JA, Coates JA, Winfield LJ, Thienthong N, Newman J, Lucent D, Ryan JH, Savage GP, Francis CL, Deadman JJ.
Rhodes DI, et al. Among authors: winfield lj.
Antivir Chem Chemother. 2011 Mar 7;21(4):155-68. doi: 10.3851/IMP1716.
Antivir Chem Chemother. 2011.
PMID: 21602613
Free article.
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