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Panaxynol, a bioactive component of American ginseng, targets macrophages and suppresses colitis in mice.
Chaparala A, Poudyal D, Tashkandi H, Witalison EE, Chumanevich AA, Hofseth JL, Nguyen I, Hardy O, Pittman DL, Wyatt MD, Windust A, Murphy EA, Nagarkatti M, Nagarkatti P, Hofseth LJ. Chaparala A, et al. Among authors: windust a. Oncotarget. 2020 Jun 2;11(22):2026-2036. doi: 10.18632/oncotarget.27592. eCollection 2020 Jun 2. Oncotarget. 2020. PMID: 32547701 Free PMC article.
American ginseng suppresses colitis through p53-mediated apoptosis of inflammatory cells.
Jin Y, Hofseth AB, Cui X, Windust AJ, Poudyal D, Chumanevich AA, Matesic LE, Singh NP, Nagarkatti M, Nagarkatti PS, Hofseth LJ. Jin Y, et al. Among authors: windust aj. Cancer Prev Res (Phila). 2010 Mar;3(3):339-47. doi: 10.1158/1940-6207.CAPR-09-0116. Epub 2010 Feb 23. Cancer Prev Res (Phila). 2010. PMID: 20179294 Free PMC article.
American ginseng suppresses inflammation and DNA damage associated with mouse colitis.
Jin Y, Kotakadi VS, Ying L, Hofseth AB, Cui X, Wood PA, Windust A, Matesic LE, Pena EA, Chiuzan C, Singh NP, Nagarkatti M, Nagarkatti PS, Wargovich MJ, Hofseth LJ. Jin Y, et al. Among authors: windust a. Carcinogenesis. 2008 Dec;29(12):2351-9. doi: 10.1093/carcin/bgn211. Epub 2008 Sep 18. Carcinogenesis. 2008. PMID: 18802031 Free PMC article.
A hexane fraction of American ginseng suppresses mouse colitis and associated colon cancer: anti-inflammatory and proapoptotic mechanisms.
Poudyal D, Le PM, Davis T, Hofseth AB, Chumanevich A, Chumanevich AA, Wargovich MJ, Nagarkatti M, Nagarkatti PS, Windust A, Hofseth LJ. Poudyal D, et al. Among authors: windust a. Cancer Prev Res (Phila). 2012 Apr;5(4):685-96. doi: 10.1158/1940-6207.CAPR-11-0421. Epub 2012 Jan 31. Cancer Prev Res (Phila). 2012. PMID: 22293630 Free PMC article.
34 results