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The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.
Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, Leinonen V, Ito A, Winblad B, Glaser E, Ankarcrona M. Hansson Petersen CA, et al. Among authors: winblad b. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13145-50. doi: 10.1073/pnas.0806192105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757748 Free PMC article.
Association of Omi/HtrA2 with γ-secretase in mitochondria.
Behbahani H, Pavlov PF, Wiehager B, Nishimura T, Winblad B, Ankarcrona M. Behbahani H, et al. Among authors: winblad b. Neurochem Int. 2010 Nov;57(6):668-75. doi: 10.1016/j.neuint.2010.08.004. Epub 2010 Aug 10. Neurochem Int. 2010. PMID: 20705111
1,200 results