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Tripeptide analogues of MG132 as protease inhibitors.
Pehere AD, Nguyen S, Garlick SK, Wilson DW, Hudson I, Sykes MJ, Morton JD, Abell AD. Pehere AD, et al. Among authors: wilson dw. Bioorg Med Chem. 2019 Jan 15;27(2):436-441. doi: 10.1016/j.bmc.2018.12.022. Epub 2018 Dec 14. Bioorg Med Chem. 2019. PMID: 30581047
Optimisation of 2-(N-phenyl carboxamide) triazolopyrimidine antimalarials with moderate to slow acting erythrocytic stage activity.
Bailey BL, Nguyen W, Ngo A, Goodman CD, Gancheva MR, Favuzza P, Sanz LM, Gamo FJ, Lowes KN, McFadden GI, Wilson DW, Laleu B, Brand S, Jackson PF, Cowman AF, Sleebs BE. Bailey BL, et al. Among authors: wilson dw. Bioorg Chem. 2021 Oct;115:105244. doi: 10.1016/j.bioorg.2021.105244. Epub 2021 Aug 8. Bioorg Chem. 2021. PMID: 34452759
Property activity refinement of 2-anilino 4-amino substituted quinazolines as antimalarials with fast acting asexual parasite activity.
Ashton TD, Ngo A, Favuzza P, Bullen HE, Gancheva MR, Romeo O, Parkyn Schneider M, Nguyen N, Steel RWJ, Duffy S, Lowes KN, Sabroux HJ, Avery VM, Boddey JA, Wilson DW, Cowman AF, Gilson PR, Sleebs BE. Ashton TD, et al. Among authors: wilson dw. Bioorg Chem. 2021 Dec;117:105359. doi: 10.1016/j.bioorg.2021.105359. Epub 2021 Sep 21. Bioorg Chem. 2021. PMID: 34689083
Retargeting azithromycin analogues to have dual-modality antimalarial activity.
Burns AL, Sleebs BE, Siddiqui G, De Paoli AE, Anderson D, Liffner B, Harvey R, Beeson JG, Creek DJ, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: wilson dw. BMC Biol. 2020 Sep 29;18(1):133. doi: 10.1186/s12915-020-00859-4. BMC Biol. 2020. PMID: 32993629 Free PMC article.
Targeting malaria parasites with novel derivatives of azithromycin.
Burns AL, Sleebs BE, Gancheva M, McLean KT, Siddiqui G, Venter H, Beeson JG, O'Handley R, Creek DJ, Ma S, Frölich S, Goodman CD, McFadden GI, Wilson DW. Burns AL, et al. Among authors: wilson dw. Front Cell Infect Microbiol. 2022 Nov 30;12:1063407. doi: 10.3389/fcimb.2022.1063407. eCollection 2022. Front Cell Infect Microbiol. 2022. PMID: 36530422 Free PMC article.
425 results