Willson TM - Search Results

1

X-ray crystal structure of the liver X receptor beta ligand binding domain: regulation by a histidine-tryptophan switch.

Williams S, Bledsoe RK, Collins JL, Boggs S, Lambert MH, Miller AB, Moore J, McKee DD, Moore L, Nichols J, Parks D, Watson M, Wisely B, Willson TM. Williams S, et al. Among authors: willson tm. J Biol Chem. 2003 Jul 18;278(29):27138-43. doi: 10.1074/jbc.M302260200. Epub 2003 May 7. J Biol Chem. 2003. PMID: 12736258 Free article.

2

An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma).

Lehmann JM, Moore LB, Smith-Oliver TA, Wilkison WO, Willson TM, Kliewer SA. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1995 Jun 2;270(22):12953-6. doi: 10.1074/jbc.270.22.12953. J Biol Chem. 1995. PMID: 7768881 Free article.

3

3-[4-(1,2-Diphenylbut-1-enyl)phenyl]acrylic acid: a non-steroidal estrogen with functional selectivity for bone over uterus in rats.

Willson TM, Henke BR, Momtahen TM, Charifson PS, Batchelor KW, Lubahn DB, Moore LB, Oliver BB, Sauls HR, Triantafillou JA, et al. Willson TM, et al. J Med Chem. 1994 May 27;37(11):1550-2. doi: 10.1021/jm00037a002. J Med Chem. 1994. PMID: 8201587 No abstract available.

4

The structure-activity relationship between peroxisome proliferator-activated receptor gamma agonism and the antihyperglycemic activity of thiazolidinediones.

Willson TM, Cobb JE, Cowan DJ, Wiethe RW, Correa ID, Prakash SR, Beck KD, Moore LB, Kliewer SA, Lehmann JM. Willson TM, et al. J Med Chem. 1996 Feb 2;39(3):665-8. doi: 10.1021/jm950395a. J Med Chem. 1996. PMID: 8576907 No abstract available.

5

Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway.

Lehmann JM, Kliewer SA, Moore LB, Smith-Oliver TA, Oliver BB, Su JL, Sundseth SS, Winegar DA, Blanchard DE, Spencer TA, Willson TM. Lehmann JM, et al. Among authors: willson tm. J Biol Chem. 1997 Feb 7;272(6):3137-40. doi: 10.1074/jbc.272.6.3137. J Biol Chem. 1997. PMID: 9013544 Free article.

6

Identification of peroxisome proliferator-activated receptor ligands from a biased chemical library.

Brown PJ, Smith-Oliver TA, Charifson PS, Tomkinson NC, Fivush AM, Sternbach DD, Wade LE, Orband-Miller L, Parks DJ, Blanchard SG, Kliewer SA, Lehmann JM, Willson TM. Brown PJ, et al. Among authors: willson tm. Chem Biol. 1997 Dec;4(12):909-18. doi: 10.1016/s1074-5521(97)90299-4. Chem Biol. 1997. PMID: 9427656

7

An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway.

Kliewer SA, Moore JT, Wade L, Staudinger JL, Watson MA, Jones SA, McKee DD, Oliver BB, Willson TM, Zetterström RH, Perlmann T, Lehmann JM. Kliewer SA, et al. Among authors: willson tm. Cell. 1998 Jan 9;92(1):73-82. doi: 10.1016/s0092-8674(00)80900-9. Cell. 1998. PMID: 9489701 Free article.

8

Cloning and characterization of human estrogen receptor beta isoforms.

Moore JT, McKee DD, Slentz-Kesler K, Moore LB, Jones SA, Horne EL, Su JL, Kliewer SA, Lehmann JM, Willson TM. Moore JT, et al. Among authors: willson tm. Biochem Biophys Res Commun. 1998 Jun 9;247(1):75-8. doi: 10.1006/bbrc.1998.8738. Biochem Biophys Res Commun. 1998. PMID: 9636657

9

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions.

Lehmann JM, McKee DD, Watson MA, Willson TM, Moore JT, Kliewer SA. Lehmann JM, et al. Among authors: willson tm. J Clin Invest. 1998 Sep 1;102(5):1016-23. doi: 10.1172/JCI3703. J Clin Invest. 1998. PMID: 9727070 Free PMC article.

10

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma.

Nolte RT, Wisely GB, Westin S, Cobb JE, Lambert MH, Kurokawa R, Rosenfeld MG, Willson TM, Glass CK, Milburn MV. Nolte RT, et al. Among authors: willson tm. Nature. 1998 Sep 10;395(6698):137-43. doi: 10.1038/25931. Nature. 1998. PMID: 9744270

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