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A resource of targeted mutant mouse lines for 5,061 genes.
Birling MC, Yoshiki A, Adams DJ, Ayabe S, Beaudet AL, Bottomley J, Bradley A, Brown SDM, Bürger A, Bushell W, Chiani F, Chin HG, Christou S, Codner GF, DeMayo FJ, Dickinson ME, Doe B, Donahue LR, Fray MD, Gambadoro A, Gao X, Gertsenstein M, Gomez-Segura A, Goodwin LO, Heaney JD, Hérault Y, de Angelis MH, Jiang ST, Justice MJ, Kasparek P, King RE, Kühn R, Lee H, Lee YJ, Liu Z, Lloyd KCK, Lorenzo I, Mallon AM, McKerlie C, Meehan TF, Fuentes VM, Newman S, Nutter LMJ, Oh GT, Pavlovic G, Ramirez-Solis R, Rosen B, Ryder EJ, Santos LA, Schick J, Seavitt JR, Sedlacek R, Seisenberger C, Seong JK, Skarnes WC, Sorg T, Steel KP, Tamura M, Tocchini-Valentini GP, Wang CL, Wardle-Jones H, Wattenhofer-Donzé M, Wells S, Wiles MV, Willis BJ, Wood JA, Wurst W, Xu Y; International Mouse Phenotyping Consortium (IMPC); Teboul L, Murray SA. Birling MC, et al. Among authors: willis bj. Nat Genet. 2021 Apr;53(4):416-419. doi: 10.1038/s41588-021-00825-y. Nat Genet. 2021. PMID: 33833456 Free PMC article.
Efficient mouse genome engineering by CRISPR-EZ technology.
Modzelewski AJ, Chen S, Willis BJ, Lloyd KCK, Wood JA, He L. Modzelewski AJ, et al. Among authors: willis bj. Nat Protoc. 2018 Jun;13(6):1253-1274. doi: 10.1038/nprot.2018.012. Epub 2018 May 10. Nat Protoc. 2018. PMID: 29748649 Free PMC article.
Generation of desminopathy in rats using CRISPR-Cas9.
Langer HT, Mossakowski AA, Willis BJ, Grimsrud KN, Wood JA, Lloyd KCK, Zbinden-Foncea H, Baar K. Langer HT, et al. Among authors: willis bj. J Cachexia Sarcopenia Muscle. 2020 Oct;11(5):1364-1376. doi: 10.1002/jcsm.12619. Epub 2020 Sep 7. J Cachexia Sarcopenia Muscle. 2020. PMID: 32893996 Free PMC article.
On the potential role of globins in brown adipose tissue: a novel conceptual model and studies in myoglobin knockout mice.
Blackburn ML, Wankhade UD, Ono-Moore KD, Chintapalli SV, Fox R, Rutkowsky JM, Willis BJ, Tolentino T, Lloyd KCK, Adams SH. Blackburn ML, et al. Among authors: willis bj. Am J Physiol Endocrinol Metab. 2021 Jul 1;321(1):E47-E62. doi: 10.1152/ajpendo.00662.2020. Epub 2021 May 10. Am J Physiol Endocrinol Metab. 2021. PMID: 33969705 Free PMC article.
Whole genome analysis for 163 gRNAs in Cas9-edited mice reveals minimal off-target activity.
Peterson KA, Khalouei S, Hanafi N, Wood JA, Lanza DG, Lintott LG, Willis BJ, Seavitt JR, Braun RE, Dickinson ME, White JK, Lloyd KCK, Heaney JD, Murray SA, Ramani A, Nutter LMJ. Peterson KA, et al. Among authors: willis bj. Commun Biol. 2023 Jun 10;6(1):626. doi: 10.1038/s42003-023-04974-0. Commun Biol. 2023. PMID: 37301944 Free PMC article.
26 results