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Epitope-focused immunogen design based on the ebolavirus glycoprotein HR2-MPER region.
Schoeder CT, Gilchuk P, Sangha AK, Ledwitch KV, Malherbe DC, Zhang X, Binshtein E, Williamson LE, Martina CE, Dong J, Armstrong E, Sutton R, Nargi R, Rodriguez J, Kuzmina N, Fiala B, King NP, Bukreyev A, Crowe JE Jr, Meiler J. Schoeder CT, et al. Among authors: williamson le. PLoS Pathog. 2022 May 18;18(5):e1010518. doi: 10.1371/journal.ppat.1010518. eCollection 2022 May. PLoS Pathog. 2022. PMID: 35584193 Free PMC article.
Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge.
Kafai NM, Williamson LE, Binshtein E, Sukupolvi-Petty S, Gardner CL, Liu J, Mackin S, Kim AS, Kose N, Carnahan RH, Jung A, Droit L, Reed DS, Handley SA, Klimstra WB, Crowe JE, Diamond MS. Kafai NM, et al. Among authors: williamson le. J Exp Med. 2022 Apr 4;219(4):e20212532. doi: 10.1084/jem.20212532. Epub 2022 Mar 17. J Exp Med. 2022. PMID: 35297953 Free PMC article.
Therapeutic alphavirus cross-reactive E1 human antibodies inhibit viral egress.
Williamson LE, Reeder KM, Bailey K, Tran MH, Roy V, Fouch ME, Kose N, Trivette A, Nargi RS, Winkler ES, Kim AS, Gainza C, Rodriguez J, Armstrong E, Sutton RE, Reidy J, Carnahan RH, McDonald WH, Schoeder CT, Klimstra WB, Davidson E, Doranz BJ, Alter G, Meiler J, Schey KL, Julander JG, Diamond MS, Crowe JE Jr. Williamson LE, et al. Cell. 2021 Aug 19;184(17):4430-4446.e22. doi: 10.1016/j.cell.2021.07.033. Cell. 2021. PMID: 34416147 Free PMC article.
Pan-protective anti-alphavirus human antibodies target a conserved E1 protein epitope.
Kim AS, Kafai NM, Winkler ES, Gilliland TC Jr, Cottle EL, Earnest JT, Jethva PN, Kaplonek P, Shah AP, Fong RH, Davidson E, Malonis RJ, Quiroz JA, Williamson LE, Vang L, Mack M, Crowe JE Jr, Doranz BJ, Lai JR, Alter G, Gross ML, Klimstra WB, Fremont DH, Diamond MS. Kim AS, et al. Among authors: williamson le. Cell. 2021 Aug 19;184(17):4414-4429.e19. doi: 10.1016/j.cell.2021.07.006. Cell. 2021. PMID: 34416146 Free PMC article.
27 results