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Linking the FTO obesity rs1421085 variant circuitry to cellular, metabolic, and organismal phenotypes in vivo.
Laber S, Forcisi S, Bentley L, Petzold J, Moritz F, Smirnov KS, Al Sadat L, Williamson I, Strobel S, Agnew T, Sengupta S, Nicol T, Grallert H, Heier M, Honecker J, Mianne J, Teboul L, Dumbell R, Long H, Simon M, Lindgren C, Bickmore WA, Hauner H, Schmitt-Kopplin P, Claussnitzer M, Cox RD. Laber S, et al. Among authors: williamson i. Sci Adv. 2021 Jul 21;7(30):eabg0108. doi: 10.1126/sciadv.abg0108. Print 2021 Jul. Sci Adv. 2021. PMID: 34290091 Free PMC article.
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5.
Sobreira DR, Joslin AC, Zhang Q, Williamson I, Hansen GT, Farris KM, Sakabe NJ, Sinnott-Armstrong N, Bozek G, Jensen-Cody SO, Flippo KH, Ober C, Bickmore WA, Potthoff M, Chen M, Claussnitzer M, Aneas I, Nóbrega MA. Sobreira DR, et al. Among authors: williamson i. Science. 2021 Jun 4;372(6546):1085-1091. doi: 10.1126/science.abf1008. Science. 2021. PMID: 34083488 Free PMC article.
MUC4 is not expressed in cell lines used for live cell imaging.
Athmane N, Williamson I, Boyle S, Biddie SC, Bickmore WA. Athmane N, et al. Among authors: williamson i. Wellcome Open Res. 2021 Nov 19;6:265. doi: 10.12688/wellcomeopenres.17229.2. eCollection 2021. Wellcome Open Res. 2021. PMID: 34796278 Free PMC article.
A central role for canonical PRC1 in shaping the 3D nuclear landscape.
Boyle S, Flyamer IM, Williamson I, Sengupta D, Bickmore WA, Illingworth RS. Boyle S, et al. Among authors: williamson i. Genes Dev. 2020 Jul 1;34(13-14):931-949. doi: 10.1101/gad.336487.120. Epub 2020 May 21. Genes Dev. 2020. PMID: 32439634 Free PMC article.
Cohesin is required for long-range enhancer action at the Shh locus.
Kane L, Williamson I, Flyamer IM, Kumar Y, Hill RE, Lettice LA, Bickmore WA. Kane L, et al. Among authors: williamson i. Nat Struct Mol Biol. 2022 Sep;29(9):891-897. doi: 10.1038/s41594-022-00821-8. Epub 2022 Sep 12. Nat Struct Mol Biol. 2022. PMID: 36097291 Free PMC article.
233 results