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An Epoxide Intermediate in Glycosidase Catalysis.
Sobala LF, Speciale G, Zhu S, Raich L, Sannikova N, Thompson AJ, Hakki Z, Lu D, Shamsi Kazem Abadi S, Lewis AR, Rojas-Cervellera V, Bernardo-Seisdedos G, Zhang Y, Millet O, Jiménez-Barbero J, Bennet AJ, Sollogoub M, Rovira C, Davies GJ, Williams SJ. Sobala LF, et al. Among authors: williams sj. ACS Cent Sci. 2020 May 27;6(5):760-770. doi: 10.1021/acscentsci.0c00111. Epub 2020 Apr 16. ACS Cent Sci. 2020. PMID: 32490192 Free PMC article.
A master of its sulfate.
Williams SJ, Davies GJ. Williams SJ, et al. Nat Struct Mol Biol. 2004 Aug;11(8):686-7. doi: 10.1038/nsmb0804-686. Nat Struct Mol Biol. 2004. PMID: 15280877 No abstract available.
Structural and mechanistic insight into N-glycan processing by endo-α-mannosidase.
Thompson AJ, Williams RJ, Hakki Z, Alonzi DS, Wennekes T, Gloster TM, Songsrirote K, Thomas-Oates JE, Wrodnigg TM, Spreitz J, Stütz AE, Butters TD, Williams SJ, Davies GJ. Thompson AJ, et al. Among authors: williams sj, williams rj. Proc Natl Acad Sci U S A. 2012 Jan 17;109(3):781-6. doi: 10.1073/pnas.1111482109. Epub 2012 Jan 4. Proc Natl Acad Sci U S A. 2012. PMID: 22219371 Free PMC article.
The reaction coordinate of a bacterial GH47 α-mannosidase: a combined quantum mechanical and structural approach.
Thompson AJ, Dabin J, Iglesias-Fernández J, Ardèvol A, Dinev Z, Williams SJ, Bande O, Siriwardena A, Moreland C, Hu TC, Smith DK, Gilbert HJ, Rovira C, Davies GJ. Thompson AJ, et al. Among authors: williams sj. Angew Chem Int Ed Engl. 2012 Oct 29;51(44):10997-1001. doi: 10.1002/anie.201205338. Epub 2012 Sep 26. Angew Chem Int Ed Engl. 2012. PMID: 23012075
Combined inhibitor free-energy landscape and structural analysis reports on the mannosidase conformational coordinate.
Williams RJ, Iglesias-Fernández J, Stepper J, Jackson A, Thompson AJ, Lowe EC, White JM, Gilbert HJ, Rovira C, Davies GJ, Williams SJ. Williams RJ, et al. Among authors: williams sj. Angew Chem Int Ed Engl. 2014 Jan 20;53(4):1087-91. doi: 10.1002/anie.201308334. Epub 2013 Dec 11. Angew Chem Int Ed Engl. 2014. PMID: 24339341 Free PMC article.
665 results