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Targeting extracellular nutrient dependencies of cancer cells.
Garcia-Bermudez J, Williams RT, Guarecuco R, Birsoy K. Garcia-Bermudez J, et al. Among authors: williams rt. Mol Metab. 2020 Mar;33:67-82. doi: 10.1016/j.molmet.2019.11.011. Epub 2019 Nov 23. Mol Metab. 2020. PMID: 31926876 Free PMC article. Review.
ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase.
Williams RT, Guarecuco R, Gates LA, Barrows D, Passarelli MC, Carey B, Baudrier L, Jeewajee S, La K, Prizer B, Malik S, Garcia-Bermudez J, Zhu XG, Cantor J, Molina H, Carroll T, Roeder RG, Abdel-Wahab O, Allis CD, Birsoy K. Williams RT, et al. Cell Metab. 2020 Apr 7;31(4):852-861.e6. doi: 10.1016/j.cmet.2020.03.008. Cell Metab. 2020. PMID: 32268116 Free PMC article.
Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxia.
Garcia-Bermudez J, Badgley MA, Prasad S, Baudrier L, Liu Y, La K, Soula M, Williams RT, Yamaguchi N, Hwang RF, Taylor LJ, de Stanchina E, Rostandy B, Alwaseem H, Molina H, Bar-Sagi D, Birsoy K. Garcia-Bermudez J, et al. Among authors: williams rt. Nat Metab. 2022 Jun;4(6):724-738. doi: 10.1038/s42255-022-00583-z. Epub 2022 Jun 20. Nat Metab. 2022. PMID: 35726024 Free PMC article.
Dietary thiamine influences l-asparaginase sensitivity in a subset of leukemia cells.
Guarecuco R, Williams RT, Baudrier L, La K, Passarelli MC, Ekizoglu N, Mestanoglu M, Alwaseem H, Rostandy B, Fidelin J, Garcia-Bermudez J, Molina H, Birsoy K. Guarecuco R, et al. Among authors: williams rt. Sci Adv. 2020 Oct 9;6(41):eabc7120. doi: 10.1126/sciadv.abc7120. Print 2020 Oct. Sci Adv. 2020. PMID: 33036978 Free PMC article.
Interferon Therapy in Myelofibrosis: Systematic Review and Meta-analysis.
Bewersdorf JP, Giri S, Wang R, Podoltsev N, Williams RT, Rampal RK, Tallman MS, Zeidan AM, Stahl M. Bewersdorf JP, et al. Among authors: williams rt. Clin Lymphoma Myeloma Leuk. 2020 Oct;20(10):e712-e723. doi: 10.1016/j.clml.2020.05.018. Epub 2020 May 28. Clin Lymphoma Myeloma Leuk. 2020. PMID: 32669244 Free PMC article.
Muscarinic receptor agonist-induced βPix binding to β-catenin promotes colon neoplasia.
Cheng K, Chahdi A, Larabee SM, Tolaymat M, Sundel MH, Drachenberg CB, Zhan M, Hu S, Said AH, Shang AC, Xie G, Alizadeh M, Moura NS, Bafford AC, Williams RT, Hanna NN, Raufman JP. Cheng K, et al. Among authors: williams rt. Sci Rep. 2023 Oct 7;13(1):16920. doi: 10.1038/s41598-023-44158-8. Sci Rep. 2023. PMID: 37805544 Free PMC article.
469 results