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Endogenous DNA 3' Blocks Are Vulnerabilities for BRCA1 and BRCA2 Deficiency and Are Reversed by the APE2 Nuclease.
Álvarez-Quilón A, Wojtaszek JL, Mathieu MC, Patel T, Appel CD, Hustedt N, Rossi SE, Wallace BD, Setiaputra D, Adam S, Ohashi Y, Melo H, Cho T, Gervais C, Muñoz IM, Grazzini E, Young JTF, Rouse J, Zinda M, Williams RS, Durocher D. Álvarez-Quilón A, et al. Among authors: williams rs. Mol Cell. 2020 Jun 18;78(6):1152-1165.e8. doi: 10.1016/j.molcel.2020.05.021. Epub 2020 Jun 8. Mol Cell. 2020. PMID: 32516598 Free PMC article.
The molecular architecture of the mammalian DNA repair enzyme, polynucleotide kinase.
Bernstein NK, Williams RS, Rakovszky ML, Cui D, Green R, Karimi-Busheri F, Mani RS, Galicia S, Koch CA, Cass CE, Durocher D, Weinfeld M, Glover JN. Bernstein NK, et al. Among authors: williams rs. Mol Cell. 2005 Mar 4;17(5):657-70. doi: 10.1016/j.molcel.2005.02.012. Mol Cell. 2005. PMID: 15749016 Free article.
Reversal of DNA damage induced Topoisomerase 2 DNA-protein crosslinks by Tdp2.
Schellenberg MJ, Perera L, Strom CN, Waters CA, Monian B, Appel CD, Vilas CK, Williams JG, Ramsden DA, Williams RS. Schellenberg MJ, et al. Among authors: williams rs, williams jg. Nucleic Acids Res. 2016 May 5;44(8):3829-44. doi: 10.1093/nar/gkw228. Epub 2016 Apr 8. Nucleic Acids Res. 2016. PMID: 27060144 Free PMC article.
APE2 Zf-GRF facilitates 3'-5' resection of DNA damage following oxidative stress.
Wallace BD, Berman Z, Mueller GA, Lin Y, Chang T, Andres SN, Wojtaszek JL, DeRose EF, Appel CD, London RE, Yan S, Williams RS. Wallace BD, et al. Among authors: williams rs. Proc Natl Acad Sci U S A. 2017 Jan 10;114(2):304-309. doi: 10.1073/pnas.1610011114. Epub 2016 Dec 27. Proc Natl Acad Sci U S A. 2017. PMID: 28028224 Free PMC article.
742 results