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[18F]-FLT positron emission tomography can be used to image the response of sensitive tumors to PI3-kinase inhibition with the novel agent GDC-0941.
Cawthorne C, Burrows N, Gieling RG, Morrow CJ, Forster D, Gregory J, Radigois M, Smigova A, Babur M, Simpson K, Hodgkinson C, Brown G, McMahon A, Dive C, Hiscock D, Wilson I, Williams KJ. Cawthorne C, et al. Among authors: williams kj. Mol Cancer Ther. 2013 May;12(5):819-28. doi: 10.1158/1535-7163.MCT-12-0905. Epub 2013 Feb 20. Mol Cancer Ther. 2013. PMID: 23427298 Free PMC article.
In vivo characterisation of a therapeutically relevant self-assembling 18 F-labelled β-sheet forming peptide and its hydrogel using positron emission tomography.
Morris O, Elsawy MA, Fairclough M, Williams KJ, Mcmahon A, Grigg J, Forster D, Miller AF, Saiani A, Prenant C. Morris O, et al. Among authors: williams kj. J Labelled Comp Radiopharm. 2017 Aug;60(10):481-488. doi: 10.1002/jlcr.3534. Epub 2017 Aug 4. J Labelled Comp Radiopharm. 2017. PMID: 28623878 Free PMC article.
Enhanced Fatty Acid Scavenging and Glycerophospholipid Metabolism Accompany Melanocyte Neoplasia Progression in Zebrafish.
Henderson F, Johnston HR, Badrock AP, Jones EA, Forster D, Nagaraju RT, Evangelou C, Kamarashev J, Green M, Fairclough M, Ramirez IB, He S, Snaar-Jagalska BE, Hollywood K, Dunn WB, Spaink HP, Smith MP, Lorigan P, Claude E, Williams KJ, McMahon AW, Hurlstone A. Henderson F, et al. Among authors: williams kj. Cancer Res. 2019 May 1;79(9):2136-2151. doi: 10.1158/0008-5472.CAN-18-2409. Epub 2019 Mar 12. Cancer Res. 2019. PMID: 30862716
Targeting the MAPK7/MMP9 axis for metastasis in primary bone cancer.
Green D, Eyre H, Singh A, Taylor JT, Chu J, Jeys L, Sumathi V, Coonar A, Rassl D, Babur M, Forster D, Alzabin S, Ponthan F, McMahon A, Bigger B, Reekie T, Kassiou M, Williams K, Dalmay T, Fraser WD, Finegan KG. Green D, et al. Oncogene. 2020 Aug;39(33):5553-5569. doi: 10.1038/s41388-020-1379-0. Epub 2020 Jul 13. Oncogene. 2020. PMID: 32655131 Free PMC article.
Anticancer chemosensitization and radiosensitization by the novel poly(ADP-ribose) polymerase-1 inhibitor AG14361.
Calabrese CR, Almassy R, Barton S, Batey MA, Calvert AH, Canan-Koch S, Durkacz BW, Hostomsky Z, Kumpf RA, Kyle S, Li J, Maegley K, Newell DR, Notarianni E, Stratford IJ, Skalitzky D, Thomas HD, Wang LZ, Webber SE, Williams KJ, Curtin NJ. Calabrese CR, et al. Among authors: williams kj. J Natl Cancer Inst. 2004 Jan 7;96(1):56-67. doi: 10.1093/jnci/djh005. J Natl Cancer Inst. 2004. PMID: 14709739
Vasoactivity of AG014699, a clinically active small molecule inhibitor of poly(ADP-ribose) polymerase: a contributory factor to chemopotentiation in vivo?
Ali M, Telfer BA, McCrudden C, O'Rourke M, Thomas HD, Kamjoo M, Kyle S, Robson T, Shaw C, Hirst DG, Curtin NJ, Williams KJ. Ali M, et al. Among authors: williams kj. Clin Cancer Res. 2009 Oct 1;15(19):6106-12. doi: 10.1158/1078-0432.CCR-09-0398. Epub 2009 Sep 29. Clin Cancer Res. 2009. PMID: 19789326 Free PMC article.
626 results