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Linking energy sensing to suppression of JAK-STAT signalling: A potential route for repurposing AMPK activators?
Pharmacol Res. 2018 Feb;128:88-100. doi: 10.1016/j.phrs.2017.10.001. Epub 2017 Oct 13.
Pharmacol Res. 2018.
PMID: 29037480
Review.
Cavin-1: caveolae-dependent signalling and cardiovascular disease.
Williams JJ, Palmer TM.
Williams JJ, et al.
Biochem Soc Trans. 2014 Apr;42(2):284-8. doi: 10.1042/BST20130270.
Biochem Soc Trans. 2014.
PMID: 24646232
Review.
Item in Clipboard
Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling.
Rutherford C, Speirs C, Williams JJ, Ewart MA, Mancini SJ, Hawley SA, Delles C, Viollet B, Costa-Pereira AP, Baillie GS, Salt IP, Palmer TM.
Rutherford C, et al.
Sci Signal. 2016 Nov 8;9(453):ra109. doi: 10.1126/scisignal.aaf8566.
Sci Signal. 2016.
PMID: 27919027
Free article.
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Targeting SOCS Proteins to Control JAK-STAT Signalling in Disease.
Durham GA, Williams JJL, Nasim MT, Palmer TM.
Durham GA, et al. Among authors: williams jjl.
Trends Pharmacol Sci. 2019 May;40(5):298-308. doi: 10.1016/j.tips.2019.03.001. Epub 2019 Apr 2.
Trends Pharmacol Sci. 2019.
PMID: 30948191
Review.
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Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3.
Williams JJ, Palmer TM.
Williams JJ, et al.
Biochem Soc Trans. 2012 Feb;40(1):215-8. doi: 10.1042/BST20110629.
Biochem Soc Trans. 2012.
PMID: 22260693
Review.
Item in Clipboard
Role of Ubiquitylation in Controlling Suppressor of Cytokine Signalling 3 (SOCS3) Function and Expression.
Williams JJ, Munro KM, Palmer TM.
Williams JJ, et al.
Cells. 2014 May 30;3(2):546-62. doi: 10.3390/cells3020546.
Cells. 2014.
PMID: 24886706
Free PMC article.
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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability.
Williams JJL, Alotaiq N, Mullen W, Burchmore R, Liu L, Baillie GS, Schaper F, Pilch PF, Palmer TM.
Williams JJL, et al.
Nat Commun. 2018 Jan 12;9(1):168. doi: 10.1038/s41467-017-02585-y.
Nat Commun. 2018.
PMID: 29330478
Free PMC article.
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Investigation of Novel Cavin-1/Suppressor of Cytokine Signaling 3 (SOCS3) Interactions by Coimmunoprecipitation, Peptide Pull-Down, and Peptide Array Overlay Approaches.
Williams JJL, Baillie GS, Palmer TM.
Williams JJL, et al.
Methods Mol Biol. 2020;2169:105-118. doi: 10.1007/978-1-0716-0732-9_10.
Methods Mol Biol. 2020.
PMID: 32548823
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