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A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease.
Canela VH, Bowen WS, Ferreira RM, Syed F, Lingeman JE, Sabo AR, Barwinska D, Winfree S, Lake BB, Cheng YH, Gaut JP, Ferkowicz M, LaFavers KA, Zhang K, Coe FL, Worcester E; Kidney Precision Medicine Project; Jain S, Eadon MT, Williams JC Jr, El-Achkar TM. Canela VH, et al. Among authors: williams jc jr. Nat Commun. 2023 Jul 19;14(1):4140. doi: 10.1038/s41467-023-38975-8. Nat Commun. 2023. PMID: 37468493 Free PMC article.
A crystallin mutant cataract with mineral deposits.
Minogue PJ, Gao J, Mathias RT, Williams JC Jr, Bledsoe SB, Sommer AJ, Beyer EC, Berthoud VM. Minogue PJ, et al. Among authors: williams jc jr. J Biol Chem. 2023 Aug;299(8):104935. doi: 10.1016/j.jbc.2023.104935. Epub 2023 Jun 17. J Biol Chem. 2023. PMID: 37331601 Free PMC article.
Integrated Cytometry With Machine Learning Applied to High-Content Imaging of Human Kidney Tissue for In Situ Cell Classification and Neighborhood Analysis.
Winfree S, McNutt AT, Khochare S, Borgard TJ, Barwinska D, Sabo AR, Ferkowicz MJ, Williams JC Jr, Lingeman JE, Gulbronson CJ, Kelly KJ, Sutton TA, Dagher PC, Eadon MT, Dunn KW, El-Achkar TM. Winfree S, et al. Among authors: williams jc jr. Lab Invest. 2023 Jun;103(6):100104. doi: 10.1016/j.labinv.2023.100104. Epub 2023 Feb 4. Lab Invest. 2023. PMID: 36867975
A user-friendly tool for cloud-based whole slide image segmentation with examples from renal histopathology.
Lutnick B, Manthey D, Becker JU, Ginley B, Moos K, Zuckerman JE, Rodrigues L, Gallan AJ, Barisoni L, Alpers CE, Wang XX, Myakala K, Jones BA, Levi M, Kopp JB, Yoshida T, Zee J, Han SS, Jain S, Rosenberg AZ, Jen KY, Sarder P; Kidney Precision Medicine Project. Lutnick B, et al. Commun Med (Lond). 2022 Aug 19;2:105. doi: 10.1038/s43856-022-00138-z. eCollection 2022. Commun Med (Lond). 2022. PMID: 35996627 Free PMC article.
Removal of Small, Asymptomatic Kidney Stones and Incidence of Relapse.
Sorensen MD, Harper JD, Borofsky MS, Hameed TA, Smoot KJ, Burke BH, Levchak BJ, Williams JC Jr, Bailey MR, Liu Z, Lingeman JE. Sorensen MD, et al. Among authors: williams jc jr. N Engl J Med. 2022 Aug 11;387(6):506-513. doi: 10.1056/NEJMoa2204253. N Engl J Med. 2022. PMID: 35947709 Free PMC article. Clinical Trial.
Connexin Mutants Cause Cataracts Through Deposition of Apatite.
Minogue PJ, Sommer AJ, Williams JC Jr, Bledsoe SB, Beyer EC, Berthoud VM. Minogue PJ, et al. Among authors: williams jc jr. Front Cell Dev Biol. 2022 Jul 22;10:951231. doi: 10.3389/fcell.2022.951231. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35938173 Free PMC article.
141 results