Williams JB - Search Results

1

Inhibition of histone methyltransferase Smyd3 rescues NMDAR and cognitive deficits in a tauopathy mouse model.

Williams JB, Cao Q, Wang W, Lee YH, Qin L, Zhong P, Ren Y, Ma K, Yan Z. Williams JB, et al. Nat Commun. 2023 Jan 6;14(1):91. doi: 10.1038/s41467-022-35749-6. Nat Commun. 2023. PMID: 36609445 Free PMC article.

2

Stress Exposure in Dopamine D4 Receptor Knockout Mice Induces Schizophrenia-Like Behaviors via Disruption of GABAergic Transmission.

Tan T, Wang W, Williams J, Ma K, Cao Q, Yan Z. Tan T, et al. Schizophr Bull. 2019 Sep 11;45(5):1012-1023. doi: 10.1093/schbul/sby163. Schizophr Bull. 2019. PMID: 30476265 Free PMC article.

3

Reversal of synaptic and behavioral deficits in a 16p11.2 duplication mouse model via restoration of the GABA synapse regulator Npas4.

Rein B, Tan T, Yang F, Wang W, Williams J, Zhang F, Mills A, Yan Z. Rein B, et al. Mol Psychiatry. 2021 Jun;26(6):1967-1979. doi: 10.1038/s41380-020-0693-9. Epub 2020 Feb 25. Mol Psychiatry. 2021. PMID: 32099100 Free PMC article.

4

Targeting histone K4 trimethylation for treatment of cognitive and synaptic deficits in mouse models of Alzheimer's disease.

Cao Q, Wang W, Williams JB, Yang F, Wang ZJ, Yan Z. Cao Q, et al. Among authors: williams jb. Sci Adv. 2020 Dec 9;6(50):eabc8096. doi: 10.1126/sciadv.abc8096. Print 2020 Dec. Sci Adv. 2020. PMID: 33298440 Free PMC article.

5

Autism risk gene KMT5B deficiency in prefrontal cortex induces synaptic dysfunction and social deficits via alterations of DNA repair and gene transcription.

Wang ZJ, Rein B, Zhong P, Williams J, Cao Q, Yang F, Zhang F, Ma K, Yan Z. Wang ZJ, et al. Neuropsychopharmacology. 2021 Aug;46(9):1617-1626. doi: 10.1038/s41386-021-01029-y. Epub 2021 May 18. Neuropsychopharmacology. 2021. PMID: 34007043 Free PMC article.

6

Transcriptomic analysis of human brains with Alzheimer's disease reveals the altered expression of synaptic genes linked to cognitive deficits.

Williams JB, Cao Q, Yan Z. Williams JB, et al. Brain Commun. 2021 Jun 3;3(3):fcab123. doi: 10.1093/braincomms/fcab123. eCollection 2021. Brain Commun. 2021. PMID: 34423299 Free PMC article.

7

Epigenetic treatment of behavioral and physiological deficits in a tauopathy mouse model.

Wang W, Cao Q, Tan T, Yang F, Williams JB, Yan Z. Wang W, et al. Among authors: williams jb. Aging Cell. 2021 Oct;20(10):e13456. doi: 10.1111/acel.13456. Epub 2021 Sep 21. Aging Cell. 2021. PMID: 34547169 Free PMC article.

8

Deficiency of autism risk factor ASH1L in prefrontal cortex induces epigenetic aberrations and seizures.

Qin L, Williams JB, Tan T, Liu T, Cao Q, Ma K, Yan Z. Qin L, et al. Among authors: williams jb. Nat Commun. 2021 Nov 15;12(1):6589. doi: 10.1038/s41467-021-26972-8. Nat Commun. 2021. PMID: 34782621 Free PMC article.

9

Targeting histone demethylase LSD1 for treatment of deficits in autism mouse models.

Rapanelli M, Williams JB, Ma K, Yang F, Zhong P, Patel R, Kumar M, Qin L, Rein B, Wang ZJ, Kassim B, Javidfar B, Couto L, Akbarian S, Yan Z. Rapanelli M, et al. Among authors: williams jb. Mol Psychiatry. 2022 Aug;27(8):3355-3366. doi: 10.1038/s41380-022-01508-8. Epub 2022 Mar 16. Mol Psychiatry. 2022. PMID: 35296809 Free PMC article.

10

A convergent mechanism of high risk factors ADNP and POGZ in neurodevelopmental disorders.

Conrow-Graham M, Williams JB, Martin J, Zhong P, Cao Q, Rein B, Yan Z. Conrow-Graham M, et al. Among authors: williams jb. Brain. 2022 Sep 14;145(9):3250-3263. doi: 10.1093/brain/awac152. Brain. 2022. PMID: 35775424 Free PMC article.

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