Williams DA - Search Results

1

Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors.

Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Bolton E, Holyoake TL, Eaves CJ, Cerny-Reiterer S, Valent P, Hochhaus A, Hughes TP, van der Kuip H, Sattler M, Wiktor-Jedrzejczak W, Richardson C, Dorrance A, Stoklosa T, Williams DA, Skorski T. Nieborowska-Skorska M, et al. Among authors: williams da. Blood. 2012 May 3;119(18):4253-63. doi: 10.1182/blood-2011-10-385658. Epub 2012 Mar 12. Blood. 2012. PMID: 22411871 Free PMC article.

2

Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.

Lane SW, De Vita S, Alexander KA, Karaman R, Milsom MD, Dorrance AM, Purdon A, Louis L, Bouxsein ML, Williams DA. Lane SW, et al. Among authors: williams da. Blood. 2012 Jan 19;119(3):736-44. doi: 10.1182/blood-2011-07-368753. Epub 2011 Nov 28. Blood. 2012. PMID: 22123845 Free PMC article.

3

Rac2 GTPase deficiency depletes BCR-ABL+ leukemic stem cells and progenitors in vivo.

Sengupta A, Arnett J, Dunn S, Williams DA, Cancelas JA. Sengupta A, et al. Among authors: williams da. Blood. 2010 Jul 8;116(1):81-4. doi: 10.1182/blood-2009-10-247437. Epub 2010 Apr 20. Blood. 2010. PMID: 20407032 Free PMC article.

4

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment.

Dorrance AM, De Vita S, Radu M, Reddy PN, McGuinness MK, Harris CE, Mathieu R, Lane SW, Kosoff R, Milsom MD, Chernoff J, Williams DA. Dorrance AM, et al. Among authors: williams da. Blood. 2013 Mar 28;121(13):2474-82. doi: 10.1182/blood-2012-10-460709. Epub 2013 Jan 18. Blood. 2013. PMID: 23335370 Free PMC article.

5

Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.

Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, Ficker AM, Dunn SK, Kuenzi AM, Arnett JL, Santho RA, Agirre X, Perentesis JP, Deininger MW, Zheng Y, Bustelo XR, Williams DA, Cancelas JA. Chang KH, et al. Among authors: williams da. Blood. 2012 Jul 26;120(4):800-11. doi: 10.1182/blood-2011-06-361709. Epub 2012 Jun 12. Blood. 2012. PMID: 22692505 Free PMC article.

6

CXCL9 inhibits eosinophil responses by a CCR3- and Rac2-dependent mechanism.

Fulkerson PC, Zhu H, Williams DA, Zimmermann N, Rothenberg ME. Fulkerson PC, et al. Among authors: williams da. Blood. 2005 Jul 15;106(2):436-43. doi: 10.1182/blood-2005-02-0489. Epub 2005 Mar 31. Blood. 2005. PMID: 15802529 Free PMC article.

7

Differential niche and Wnt requirements during acute myeloid leukemia progression.

Lane SW, Wang YJ, Lo Celso C, Ragu C, Bullinger L, Sykes SM, Ferraro F, Shterental S, Lin CP, Gilliland DG, Scadden DT, Armstrong SA, Williams DA. Lane SW, et al. Among authors: williams da. Blood. 2011 Sep 8;118(10):2849-56. doi: 10.1182/blood-2011-03-345165. Epub 2011 Jul 15. Blood. 2011. PMID: 21765021 Free PMC article.

8

The FIP1L1-PDGFRA fusion gene cooperates with IL-5 to induce murine hypereosinophilic syndrome (HES)/chronic eosinophilic leukemia (CEL)-like disease.

Yamada Y, Rothenberg ME, Lee AW, Akei HS, Brandt EB, Williams DA, Cancelas JA. Yamada Y, et al. Among authors: williams da. Blood. 2006 May 15;107(10):4071-9. doi: 10.1182/blood-2005-08-3153. Epub 2006 Jan 17. Blood. 2006. PMID: 16418325 Free PMC article.

9

FIP1L1/PDGFRalpha synergizes with SCF to induce systemic mastocytosis in a murine model of chronic eosinophilic leukemia/hypereosinophilic syndrome.

Yamada Y, Sanchez-Aguilera A, Brandt EB, McBride M, Al-Moamen NJ, Finkelman FD, Williams DA, Cancelas JA, Rothenberg ME. Yamada Y, et al. Among authors: williams da. Blood. 2008 Sep 15;112(6):2500-7. doi: 10.1182/blood-2007-11-126268. Epub 2008 Jun 6. Blood. 2008. PMID: 18539901 Free article.

10

Rac GTPase isoforms Rac1 and Rac2 play a redundant and crucial role in T-cell development.

Guo F, Cancelas JA, Hildeman D, Williams DA, Zheng Y. Guo F, et al. Among authors: williams da. Blood. 2008 Sep 1;112(5):1767-75. doi: 10.1182/blood-2008-01-132068. Epub 2008 Jun 25. Blood. 2008. PMID: 18579797 Free PMC article.

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