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Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein.
Zhang S, Zhu R, Pan B, Xu H, Olufemi MF, Gathagan RJ, Li Y, Zhang L, Zhang J, Xiang W, Kagan EM, Cao X, Yuan C, Kim SJ, Williams CK, Magaki S, Vinters HV, Lashuel HA, Garcia BA, James Petersson E, Trojanowski JQ, Lee VM, Peng C. Zhang S, et al. Among authors: williams ck. Nat Neurosci. 2023 Feb;26(2):213-225. doi: 10.1038/s41593-022-01239-7. Epub 2023 Jan 23. Nat Neurosci. 2023. PMID: 36690898 Free PMC article.
Small molecules disaggregate alpha-synuclein and prevent seeding from patient brain-derived fibrils.
Murray KA, Hu CJ, Pan H, Lu J, Abskharon R, Bowler JT, Rosenberg GM, Williams CK, Elezi G, Balbirnie M, Faull KF, Vinters HV, Seidler PM, Eisenberg DS. Murray KA, et al. Among authors: williams ck. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2217835120. doi: 10.1073/pnas.2217835120. Epub 2023 Feb 9. Proc Natl Acad Sci U S A. 2023. PMID: 36757890 Free PMC article.
Author Correction: Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein.
Zhang S, Zhu R, Pan B, Xu H, Olufemi MF, Gathagan RJ, Li Y, Zhang L, Zhang J, Xiang W, Kagan EM, Cao X, Yuan C, Kim SJ, Williams CK, Magaki S, Vinters HV, Lashuel HA, Garcia BA, James Petersson E, Trojanowski JQ, Lee VM, Peng C. Zhang S, et al. Among authors: williams ck. Nat Neurosci. 2023 Dec;26(12):2250. doi: 10.1038/s41593-023-01474-6. Nat Neurosci. 2023. PMID: 37814027 No abstract available.
Intercellular Signaling Pathways as Therapeutic Targets for Vascular Dementia Repair.
Tian M, Kawaguchi R, Shen Y, Machnicki M, Villegas NG, Cooper DR, Montgomery N, Haring J, Lan R, Yuan AH, Williams CK, Magaki S, Vinters HV, Zhang Y, De Biase LM, Silva AJ, Carmichael ST. Tian M, et al. Among authors: williams ck. bioRxiv [Preprint]. 2024 Mar 27:2024.03.24.585301. doi: 10.1101/2024.03.24.585301. bioRxiv. 2024. PMID: 38585718 Free PMC article. Preprint.
HIV and COVID-19: two pandemics with significant (but different) central nervous system complications.
Magaki S, Zhang T, Han K, Hilda M, Yong WH, Achim C, Fishbein G, Fishbein MC, Garner O, Salamon N, Williams CK, Valdes-Sueiras MA, Hsu JJ, Kelesidis T, Mathisen GE, Lavretsky H, Singer EJ, Vinters HV. Magaki S, et al. Among authors: williams ck. Free Neuropathol. 2024 Mar 5;5:5-5. doi: 10.17879/freeneuropathology-2024-5343. eCollection 2024 Jan. Free Neuropathol. 2024. PMID: 38469363 Free PMC article.
267 results