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Inhibiting pyrimidine biosynthesis impairs Ebola virus replication through depletion of nucleoside pools and activation of innate immune responses.
Luthra P, Naidoo J, Pietzsch CA, De S, Khadka S, Anantpadma M, Williams CG, Edwards MR, Davey RA, Bukreyev A, Ready JM, Basler CF. Luthra P, et al. Among authors: williams cg. Antiviral Res. 2018 Oct;158:288-302. doi: 10.1016/j.antiviral.2018.08.012. Epub 2018 Aug 23. Antiviral Res. 2018. PMID: 30144461 Free PMC article.
Non-canonical proline-tyrosine interactions with multiple host proteins regulate Ebola virus infection.
Batra J, Mori H, Small GI, Anantpadma M, Shtanko O, Mishra N, Zhang M, Liu D, Williams CG, Biedenkopf N, Becker S, Gross ML, Leung DW, Davey RA, Amarasinghe GK, Krogan NJ, Basler CF. Batra J, et al. Among authors: williams cg. EMBO J. 2021 Sep 15;40(18):e105658. doi: 10.15252/embj.2020105658. Epub 2021 Aug 2. EMBO J. 2021. PMID: 34260076 Free PMC article.
Synthesis and antiviral activity of fatty acyl conjugates of remdesivir against severe acute respiratory syndrome coronavirus 2 and Ebola virus.
El-Sayed NS, Jureka AS, Edwards MR, Lohan S, Williams CG, Keiser PT, Davey RA, Totonchy J, Tiwari RK, Basler CF, Parang K. El-Sayed NS, et al. Among authors: williams cg. Eur J Med Chem. 2021 Dec 15;226:113862. doi: 10.1016/j.ejmech.2021.113862. Epub 2021 Sep 21. Eur J Med Chem. 2021. PMID: 34583312 Free PMC article.
Metabolic immaturity of newborns and breast milk bile acid metabolites are the central determinants of heightened neonatal vulnerability to norovirus diarrhea.
Peiper AM, Aparicio JM, Phophi L, Hu Z, Helm EW, Phillips M, Williams CG, Subramanian S, Cross M, Iyer N, Nguyen Q, Newsome R, Jobin C, Langel SN, Bucardo F, Becker-Dreps S, Tan XD, Dawson PA, Karst SM. Peiper AM, et al. Among authors: williams cg. bioRxiv [Preprint]. 2024 May 1:2024.05.01.592031. doi: 10.1101/2024.05.01.592031. bioRxiv. 2024. PMID: 38746153 Free PMC article. Preprint.
160 results