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Determination of the Pharmacokinetics and Pharmacodynamics of Isoniazid, Rifampicin, Pyrazinamide and Ethambutol in a Cross-Over Cynomolgus Macaque Model of Mycobacterium tuberculosis Infection.
Sibley L, White AD, Sarfas C, Gullick J, Gleeson F, Lanni F, Clark S, Rayner E, Ferrer-Bazaga S, Ortega-Muro F, Alameda L, Rullas J, Sousa V, Martinez M, Angulo-Barturen I, Garcia A, Vaquero JJ, Pertinez HE, Davies G, Dennis M, Williams A, Sharpe S. Sibley L, et al. Among authors: williams a. Pharmaceutics. 2022 Nov 30;14(12):2666. doi: 10.3390/pharmaceutics14122666. Pharmaceutics. 2022. PMID: 36559163 Free PMC article.
Evaluation of vaccines in the EU TB Vaccine Cluster using a guinea pig aerosol infection model of tuberculosis.
Williams A, Hatch GJ, Clark SO, Gooch KE, Hatch KA, Hall GA, Huygen K, Ottenhoff TH, Franken KL, Andersen P, Doherty TM, Kaufmann SH, Grode L, Seiler P, Martin C, Gicquel B, Cole ST, Brodin P, Pym AS, Dalemans W, Cohen J, Lobet Y, Goonetilleke N, McShane H, Hill A, Parish T, Smith D, Stoker NG, Lowrie DB, Källenius G, Svenson S, Pawlowski A, Blake K, Marsh PD. Williams A, et al. Tuberculosis (Edinb). 2005 Jan-Mar;85(1-2):29-38. doi: 10.1016/j.tube.2004.09.009. Epub 2005 Jan 20. Tuberculosis (Edinb). 2005. PMID: 15687025
Assessment of different formulations of oral Mycobacterium bovis Bacille Calmette-Guérin (BCG) vaccine in rodent models for immunogenicity and protection against aerosol challenge with M. bovis.
Clark S, Cross ML, Smith A, Court P, Vipond J, Nadian A, Hewinson RG, Batchelor HK, Perrie Y, Williams A, Aldwell FE, Chambers MA. Clark S, et al. Among authors: williams a. Vaccine. 2008 Oct 29;26(46):5791-7. doi: 10.1016/j.vaccine.2008.08.028. Epub 2008 Sep 26. Vaccine. 2008. PMID: 18789366
Determination of lesion volume by MRI and stereology in a macaque model of tuberculosis.
Sharpe SA, Eschelbach E, Basaraba RJ, Gleeson F, Hall GA, McIntyre A, Williams A, Kraft SL, Clark S, Gooch K, Hatch G, Orme IM, Marsh PD, Dennis MJ. Sharpe SA, et al. Among authors: williams a. Tuberculosis (Edinb). 2009 Nov;89(6):405-16. doi: 10.1016/j.tube.2009.09.002. Epub 2009 Oct 30. Tuberculosis (Edinb). 2009. PMID: 19879805
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