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VEXAS syndrome is characterized by inflammasome activation and monocyte dysregulation.
Kosmider O, Possémé C, Templé M, Corneau A, Carbone F, Duroyon E, Breillat P, Chirayath TW, Oules B, Sohier P, Luka M, Gobeaux C, Lazaro E, Outh R, Le Guenno G, Lifermann F, Berleur M, Le Mene M, Friedrich C, Lenormand C, Weitten T, Guillotin V, Burroni B, Boussier J, Willems L, Aractingi S, Dionet L, Tharaux PL, Vergier B, Raynaud P, Ea HK, Ménager M, Duffy D, Terrier B. Kosmider O, et al. Among authors: willems l. Nat Commun. 2024 Jan 30;15(1):910. doi: 10.1038/s41467-024-44811-4. Nat Commun. 2024. PMID: 38291039 Free PMC article.
APG101 efficiently rescues erythropoiesis in lower risk myelodysplastic syndromes with severe impairment of hematopoiesis.
Raimbault A, Pierre-Eugene C, Rouquette A, Deudon C, Willems L, Chapuis N, Mathis S, Kunz C, Fricke H, Kosmider O, Bardet V, Fontenay M; Groupe Francophone des Myélodysplasies. Raimbault A, et al. Among authors: willems l. Oncotarget. 2016 Mar 22;7(12):14898-911. doi: 10.18632/oncotarget.7469. Oncotarget. 2016. PMID: 26910909 Free PMC article.
The fraction of CD117/c-KIT-expressing erythroid precursors predicts ESA response in low-risk myelodysplastic syndromes.
Raimbault A, Itzykson R, Willems L, Rousseau A, Chapuis N, Mathis S, Clauser S, Radford-Weiss I, Bouscary D, Fontenay M, Kosmider O, Bardet V. Raimbault A, et al. Among authors: willems l. Cytometry B Clin Cytom. 2019 May;96(3):215-222. doi: 10.1002/cyto.b.21781. Epub 2019 Apr 9. Cytometry B Clin Cytom. 2019. PMID: 30963682 Free article.
Phenotypic landscape of granulocytes and monocytes by multiparametric flow cytometry: A prospective study of a 1-tube panel strategy for diagnosis and prognosis of patients with MDS.
Barreau S, Green AS, Dussiau C, Alary AS, Raimbault A, Mathis S, Willems L, Bouscary D, Kosmider O, Bardet V, Fontenay M, Chapuis N. Barreau S, et al. Among authors: willems l. Cytometry B Clin Cytom. 2020 May;98(3):226-237. doi: 10.1002/cyto.b.21843. Epub 2019 Sep 9. Cytometry B Clin Cytom. 2020. PMID: 31498561 Free article.
Improvement of therapy-induced myelodysplastic syndrome by infusion of autologous CD34-positive hematopoietic progenitor cells without chemotherapy.
Alary AS, Vignon M, Carapito R, Halabi N, Willems L, Green A, Chapuis N, Heshmati F, Cuccuini W, Kaltenbach S, Radford-Weiss I, Kosmider O, Bouscary D, Bahram S, Rafii A, Tamburini J. Alary AS, et al. Among authors: willems l. Leuk Lymphoma. 2020 Dec;61(13):3259-3262. doi: 10.1080/10428194.2020.1804562. Epub 2020 Aug 28. Leuk Lymphoma. 2020. PMID: 32856491 No abstract available.
Venetoclax combination therapy induces deep AML remission with eradication of leukemic stem cells and remodeling of clonal haematopoiesis.
Vazquez R, Breal C, Zalmai L, Friedrich C, Almire C, Contejean A, Barreau S, Grignano E, Willems L, Deau-Fischer B, Franchi P, Vignon M, Decroocq J, Birsen R, Goldwirt L, Kaltenbach S, Couronne L, Fontenay M, Kosmider O, Bouscary D, Chapuis N. Vazquez R, et al. Among authors: willems l. Blood Cancer J. 2021 Mar 19;11(3):62. doi: 10.1038/s41408-021-00448-w. Blood Cancer J. 2021. PMID: 33741892 Free PMC article. No abstract available.
Reduced peripheral blood dendritic cell and monocyte subsets in MDS patients with systemic inflammatory or dysimmune diseases.
Jachiet V, Ricard L, Hirsch P, Malard F, Pascal L, Beyne-Rauzy O, Peterlin P, Maria ATJ, Vey N, D'Aveni M, Gourin MP, Dimicoli-Salazar S, Banos A, Wickenhauser S, Terriou L, De Renzis B, Durot E, Natarajan-Ame S, Vekhoff A, Voillat L, Park S, Vinit J, Dieval C, Dellal A, Grobost V, Willems L, Rossignol J, Solary E, Kosmider O, Dulphy N, Zhao LP, Adès L, Fenaux P, Fain O, Mohty M, Gaugler B, Mekinian A; MINHEMON: French Network of dysimmune disorders associated with hemopathies. Jachiet V, et al. Among authors: willems l. Clin Exp Med. 2023 Jul;23(3):803-813. doi: 10.1007/s10238-022-00866-5. Epub 2022 Aug 11. Clin Exp Med. 2023. PMID: 35953763
598 results