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Valproate activates bovine leukemia virus gene expression, triggers apoptosis, and induces leukemia/lymphoma regression in vivo.
Achachi A, Florins A, Gillet N, Debacq C, Urbain P, Foutsop GM, Vandermeers F, Jasik A, Reichert M, Kerkhofs P, Lagneaux L, Burny A, Kettmann R, Willems L. Achachi A, et al. Among authors: willems l. Proc Natl Acad Sci U S A. 2005 Jul 19;102(29):10309-14. doi: 10.1073/pnas.0504248102. Epub 2005 Jul 8. Proc Natl Acad Sci U S A. 2005. PMID: 16006517 Free PMC article.
Peripheral blood B-cell death compensates for excessive proliferation in lymphoid tissues and maintains homeostasis in bovine leukemia virus-infected sheep.
Debacq C, Gillet N, Asquith B, Sanchez-Alcaraz MT, Florins A, Boxus M, Schwartz-Cornil I, Bonneau M, Jean G, Kerkhofs P, Hay J, Théwis A, Kettmann R, Willems L. Debacq C, et al. Among authors: willems l. J Virol. 2006 Oct;80(19):9710-9. doi: 10.1128/JVI.01022-06. J Virol. 2006. PMID: 16973575 Free PMC article.
Cell dynamics and immune response to BLV infection: a unifying model.
Florins A, Gillet N, Asquith B, Boxus M, Burteau C, Twizere JC, Urbain P, Vandermeers F, Debacq C, Sanchez-Alcaraz MT, Schwartz-Cornil I, Kerkhofs P, Jean G, Théwis A, Hay J, Mortreux F, Wattel E, Reichert M, Burny A, Kettmann R, Bangham C, Willems L. Florins A, et al. Among authors: willems l. Front Biosci. 2007 Jan 1;12:1520-31. doi: 10.2741/2165. Front Biosci. 2007. PMID: 17127399 Free article. Review.
Valproic acid induces apoptosis in chronic lymphocytic leukemia cells through activation of the death receptor pathway and potentiates TRAIL response.
Lagneaux L, Gillet N, Stamatopoulos B, Delforge A, Dejeneffe M, Massy M, Meuleman N, Kentos A, Martiat P, Willems L, Bron D. Lagneaux L, et al. Among authors: willems l. Exp Hematol. 2007 Oct;35(10):1527-37. doi: 10.1016/j.exphem.2007.06.014. Epub 2007 Aug 13. Exp Hematol. 2007. PMID: 17697742 Free article.
Histone deacetylase mediated transcriptional activation reduces proviral loads in HTLV-1 associated myelopathy/tropical spastic paraparesis patients.
Lezin A, Gillet N, Olindo S, Signaté A, Grandvaux N, Verlaeten O, Belrose G, de Carvalho Bittencourt M, Hiscott J, Asquith B, Burny A, Smadja D, Césaire R, Willems L. Lezin A, et al. Among authors: willems l. Blood. 2007 Nov 15;110(10):3722-8. doi: 10.1182/blood-2007-04-085076. Epub 2007 Aug 23. Blood. 2007. PMID: 17717136 Free article.
598 results