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Gla-rich protein acts as a calcification inhibitor in the human cardiovascular system.
Viegas CS, Rafael MS, Enriquez JL, Teixeira A, Vitorino R, Luís IM, Costa RM, Santos S, Cavaco S, Neves J, Macedo AL, Willems BA, Vermeer C, Simes DC. Viegas CS, et al. Among authors: willems ba. Arterioscler Thromb Vasc Biol. 2015 Feb;35(2):399-408. doi: 10.1161/ATVBAHA.114.304823. Epub 2014 Dec 23. Arterioscler Thromb Vasc Biol. 2015. PMID: 25538207
Nicotine promotes vascular calcification via intracellular Ca2+-mediated, Nox5-induced oxidative stress, and extracellular vesicle release in vascular smooth muscle cells.
Petsophonsakul P, Burgmaier M, Willems B, Heeneman S, Stadler N, Gremse F, Reith S, Burgmaier K, Kahles F, Marx N, Natour E, Bidar E, Jacobs M, Mees B, Reutelingsperger C, Furmanik M, Schurgers L. Petsophonsakul P, et al. Cardiovasc Res. 2022 Jul 20;118(9):2196-2210. doi: 10.1093/cvr/cvab244. Cardiovasc Res. 2022. PMID: 34273166 Free PMC article.
Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification.
Furmanik M, Chatrou M, van Gorp R, Akbulut A, Willems B, Schmidt H, van Eys G, Bochaton-Piallat ML, Proudfoot D, Biessen E, Hedin U, Perisic L, Mees B, Shanahan C, Reutelingsperger C, Schurgers L. Furmanik M, et al. Circ Res. 2020 Sep 11;127(7):911-927. doi: 10.1161/CIRCRESAHA.119.316159. Epub 2020 Jun 22. Circ Res. 2020. PMID: 32564697
AnxA5 reduces plaque inflammation of advanced atherosclerotic lesions in apoE(-/-) mice.
Burgmaier M, Schutters K, Willems B, van der Vorst EP, Kusters D, Chatrou M, Norling L, Biessen EA, Cleutjens J, Perretti M, Schurgers LJ, Reutelingsperger CP. Burgmaier M, et al. J Cell Mol Med. 2014 Oct;18(10):2117-24. doi: 10.1111/jcmm.12374. Epub 2014 Sep 12. J Cell Mol Med. 2014. PMID: 25214012 Free PMC article.
Smokers can learn to influence their urge to smoke.
Dols M, Willems B, van den Hout M, Bittoun R. Dols M, et al. Addict Behav. 2000 Jan-Feb;25(1):103-8. doi: 10.1016/s0306-4603(98)00115-4. Addict Behav. 2000. PMID: 10708324 Clinical Trial.
11 results