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Page 1
Genes contributing to prion pathogenesis.
Tamgüney G, Giles K, Glidden DV, Lessard P, Wille H, Tremblay P, Groth DF, Yehiely F, Korth C, Moore RC, Tatzelt J, Rubinstein E, Boucheix C, Yang X, Stanley P, Lisanti MP, Dwek RA, Rudd PM, Moskovitz J, Epstein CJ, Cruz TD, Kuziel WA, Maeda N, Sap J, Ashe KH, Carlson GA, Tesseur I, Wyss-Coray T, Mucke L, Weisgraber KH, Mahley RW, Cohen FE, Prusiner SB. Tamgüney G, et al. Among authors: wille h. J Gen Virol. 2008 Jul;89(Pt 7):1777-1788. doi: 10.1099/vir.0.2008/001255-0. J Gen Virol. 2008. PMID: 18559949 Free PMC article.
Octarepeat region flexibility impacts prion function, endoproteolysis and disease manifestation.
Lau A, McDonald A, Daude N, Mays CE, Walter ED, Aglietti R, Mercer RC, Wohlgemuth S, van der Merwe J, Yang J, Gapeshina H, Kim C, Grams J, Shi B, Wille H, Balachandran A, Schmitt-Ulms G, Safar JG, Millhauser GL, Westaway D. Lau A, et al. Among authors: wille h. EMBO Mol Med. 2015 Mar;7(3):339-56. doi: 10.15252/emmm.201404588. EMBO Mol Med. 2015. PMID: 25661904 Free PMC article.
A Neuronal Culture System to Detect Prion Synaptotoxicity.
Fang C, Imberdis T, Garza MC, Wille H, Harris DA. Fang C, et al. Among authors: wille h. PLoS Pathog. 2016 May 26;12(5):e1005623. doi: 10.1371/journal.ppat.1005623. eCollection 2016 May. PLoS Pathog. 2016. PMID: 27227882 Free PMC article.
A novel Gerstmann-Sträussler-Scheinker disease mutation defines a precursor for amyloidogenic 8 kDa PrP fragments and reveals N-terminal structural changes shared by other GSS alleles.
Mercer RCC, Daude N, Dorosh L, Fu ZL, Mays CE, Gapeshina H, Wohlgemuth SL, Acevedo-Morantes CY, Yang J, Cashman NR, Coulthart MB, Pearson DM, Joseph JT, Wille H, Safar JG, Jansen GH, Stepanova M, Sykes BD, Westaway D. Mercer RCC, et al. Among authors: wille h. PLoS Pathog. 2018 Jan 16;14(1):e1006826. doi: 10.1371/journal.ppat.1006826. eCollection 2018 Jan. PLoS Pathog. 2018. PMID: 29338055 Free PMC article.
Isolation of infectious, non-fibrillar and oligomeric prions from a genetic prion disease.
Vanni I, Pirisinu L, Acevedo-Morantes C, Kamali-Jamil R, Rathod V, Di Bari MA, D'Agostino C, Marcon S, Esposito E, Riccardi G, Hornemann S, Senatore A, Aguzzi A, Agrimi U, Wille H, Nonno R. Vanni I, et al. Among authors: wille h. Brain. 2020 May 1;143(5):1512-1524. doi: 10.1093/brain/awaa078. Brain. 2020. PMID: 32303068 Free PMC article.
211 results