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1,169 results

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Page 1
A novel IgE-neutralizing antibody for the treatment of severe uncontrolled asthma.
Cohen ES, Dobson CL, Käck H, Wang B, Sims DA, Lloyd CO, England E, Rees DG, Guo H, Karagiannis SN, O'Brien S, Persdotter S, Ekdahl H, Butler R, Keyes F, Oakley S, Carlsson M, Briend E, Wilkinson T, Anderson IK, Monk PD, von Wachenfeldt K, Eriksson PO, Gould HJ, Vaughan TJ, May RD. Cohen ES, et al. Among authors: wilkinson t. MAbs. 2014 May-Jun;6(3):756-64. doi: 10.4161/mabs.28394. Epub 2014 Feb 28. MAbs. 2014. PMID: 24583620 Free PMC article.
Protein engineering and preclinical development of a GM-CSF receptor antibody for the treatment of rheumatoid arthritis.
Minter RR, Cohen ES, Wang B, Liang M, Vainshtein I, Rees G, Eghobamien L, Harrison P, Sims DA, Matthews C, Wilkinson T, Monk P, Drinkwater C, Fabri L, Nash A, McCourt M, Jermutus L, Roskos L, Anderson IK, Sleeman MA. Minter RR, et al. Among authors: wilkinson t. Br J Pharmacol. 2013 Jan;168(1):200-11. doi: 10.1111/j.1476-5381.2012.02173.x. Br J Pharmacol. 2013. PMID: 22913645 Free PMC article.
Generation of potent mouse monoclonal antibodies to self-proteins using T-cell epitope "tags".
Percival-Alwyn JL, England E, Kemp B, Rapley L, Davis NH, McCarthy GR, Majithiya JB, Corkill DJ, Welsted S, Minton K, Cohen ES, Robinson MJ, Dobson C, Wilkinson TC, Vaughan TJ, Groves MA, Tigue NJ. Percival-Alwyn JL, et al. Among authors: wilkinson tc. MAbs. 2015;7(1):129-37. doi: 10.4161/19420862.2014.985489. MAbs. 2015. PMID: 25523454 Free PMC article.
Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
Colley CS, Popovic B, Sridharan S, Debreczeni JE, Hargeaves D, Fung M, An LL, Edwards B, Arnold J, England E, Eghobamien L, Sivars U, Flavell L, Renshaw J, Wickson K, Warrener P, Zha J, Bonnell J, Woods R, Wilkinson T, Dobson C, Vaughan TJ. Colley CS, et al. Among authors: wilkinson t. MAbs. 2018 Jan;10(1):104-117. doi: 10.1080/19420862.2017.1384892. Epub 2017 Oct 24. MAbs. 2018. PMID: 28952876 Free PMC article.
Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1.
Douthwaite JA, Sridharan S, Huntington C, Hammersley J, Marwood R, Hakulinen JK, Ek M, Sjögren T, Rider D, Privezentzev C, Seaman JC, Cariuk P, Knights V, Young J, Wilkinson T, Sleeman M, Finch DK, Lowe DC, Vaughan TJ. Douthwaite JA, et al. Among authors: wilkinson t. MAbs. 2015;7(1):152-66. doi: 10.4161/19420862.2014.985158. MAbs. 2015. PMID: 25484051 Free PMC article.
Isolation of Potent CGRP Neutralizing Antibodies Using Four Simple Assays.
Neal F, Arnold J, Rossant CJ, Podichetty S, Lowne D, Dobson C, Wilkinson T, Colley C, Howes R, Vaughan TJ. Neal F, et al. Among authors: wilkinson t. J Biomol Screen. 2016 Jan;21(1):24-34. doi: 10.1177/1087057115610070. Epub 2015 Oct 8. J Biomol Screen. 2016. PMID: 26450103
Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2.
Popovic B, Breed J, Rees DG, Gardener MJ, Vinall LM, Kemp B, Spooner J, Keen J, Minter R, Uddin F, Colice G, Wilkinson T, Vaughan T, May RD. Popovic B, et al. Among authors: wilkinson t. J Mol Biol. 2017 Jan 20;429(2):208-219. doi: 10.1016/j.jmb.2016.12.005. Epub 2016 Dec 9. J Mol Biol. 2017. PMID: 27956146 Free article.
Discovery and characterisation of an antibody that selectively modulates the inhibitory activity of plasminogen activator inhibitor-1.
Vousden KA, Lundqvist T, Popovic B, Naiman B, Carruthers AM, Newton P, Johnson DJD, Pomowski A, Wilkinson T, Dufner P, de Mendez I, Mallinder PR, Murray C, Strain M, Connor J, Murray LA, Sleeman MA, Lowe DC, Huntington JA, Vaughan TJ. Vousden KA, et al. Among authors: wilkinson t. Sci Rep. 2019 Feb 7;9(1):1605. doi: 10.1038/s41598-019-38842-x. Sci Rep. 2019. PMID: 30733557 Free PMC article.
Development of a homogeneous high-throughput screening assay for biological inhibitors of human rhinovirus infection.
Newton P, O'Shea D, Wells E, Moakes K, Dunmore R, Butler RJ, Wilkinson T, Ward A, Casson N, Strain M, Vousden K, Lowe DC, Pattison DV, Carruthers AM, Sleeman MA, Vaughan TJ, Harrison P. Newton P, et al. Among authors: wilkinson t. J Biomol Screen. 2013 Mar;18(3):237-46. doi: 10.1177/1087057112469047. Epub 2012 Dec 3. J Biomol Screen. 2013. PMID: 23207740
1,169 results