Wilkinson MC - Search Results

1

Anticoagulant Activity of Naja nigricollis Venom Is Mediated by Phospholipase A2 Toxins and Inhibited by Varespladib.

Kazandjian TD, Arrahman A, Still KBM, Somsen GW, Vonk FJ, Casewell NR, Wilkinson MC, Kool J. Kazandjian TD, et al. Among authors: wilkinson mc. Toxins (Basel). 2021 Apr 23;13(5):302. doi: 10.3390/toxins13050302. Toxins (Basel). 2021. PMID: 33922825 Free PMC article.

2

Preclinical validation of a repurposed metal chelator as an early-intervention therapeutic for hemotoxic snakebite.

Albulescu LO, Hale MS, Ainsworth S, Alsolaiss J, Crittenden E, Calvete JJ, Evans C, Wilkinson MC, Harrison RA, Kool J, Casewell NR. Albulescu LO, et al. Among authors: wilkinson mc. Sci Transl Med. 2020 May 6;12(542):eaay8314. doi: 10.1126/scitranslmed.aay8314. Sci Transl Med. 2020. PMID: 32376771 Free PMC article.

3

Physiological constraints dictate toxin spatial heterogeneity in snake venom glands.

Kazandjian TD, Hamilton BR, Robinson SD, Hall SR, Bartlett KE, Rowley P, Wilkinson MC, Casewell NR, Undheim EAB. Kazandjian TD, et al. Among authors: wilkinson mc. BMC Biol. 2022 Jun 27;20(1):148. doi: 10.1186/s12915-022-01350-y. BMC Biol. 2022. PMID: 35761243 Free PMC article.

4

Virus-like particles displaying conserved toxin epitopes stimulate polyspecific, murine antibody responses capable of snake venom recognition.

Menzies SK, Dawson CA, Crittenden E, Edge RJ, Hall SR, Alsolaiss J, Wilkinson MC, Casewell NR, Harrison RA, Ainsworth S. Menzies SK, et al. Among authors: wilkinson mc. Sci Rep. 2022 Jul 5;12(1):11328. doi: 10.1038/s41598-022-13376-x. Sci Rep. 2022. PMID: 35790745 Free PMC article.

5

Exploring the Utility of Recombinant Snake Venom Serine Protease Toxins as Immunogens for Generating Experimental Snakebite Antivenoms.

Alomran N, Blundell P, Alsolaiss J, Crittenden E, Ainsworth S, Dawson CA, Edge RJ, Hall SR, Harrison RA, Wilkinson MC, Menzies SK, Casewell NR. Alomran N, et al. Among authors: wilkinson mc. Toxins (Basel). 2022 Jun 29;14(7):443. doi: 10.3390/toxins14070443. Toxins (Basel). 2022. PMID: 35878181 Free PMC article.

6

African polyvalent antivenom can maintain pharmacological stability and ability to neutralise murine venom lethality for decades post-expiry: evidence for increasing antivenom shelf life to aid in alleviating chronic shortages.

Solano G, Cunningham S, Edge RJ, Duran G, Sanchez A, Villalta M, Clare RH, Wilkinson MC, Marriott AE, Abada C, Menzies SK, Keen M, Lalloo DG, Stienstra Y, Abouyannis M, Casewell NR, León G, Ainsworth S. Solano G, et al. Among authors: wilkinson mc. BMJ Glob Health. 2024 Mar 13;9(3):e014813. doi: 10.1136/bmjgh-2023-014813. BMJ Glob Health. 2024. PMID: 38485142 Free PMC article.

7

Dermonecrosis caused by a spitting cobra snakebite results from toxin potentiation and is prevented by the repurposed drug varespladib.

Bartlett KE, Hall SR, Rasmussen SA, Crittenden E, Dawson CA, Albulescu LO, Laprade W, Harrison RA, Saviola AJ, Modahl CM, Jenkins TP, Wilkinson MC, Gutiérrez JM, Casewell NR. Bartlett KE, et al. Among authors: wilkinson mc. Proc Natl Acad Sci U S A. 2024 May 7;121(19):e2315597121. doi: 10.1073/pnas.2315597121. Epub 2024 Apr 30. Proc Natl Acad Sci U S A. 2024. PMID: 38687786 Free article.

8

Molecular characterisation of endogenous snake venom metalloproteinase inhibitors.

Wagstaff SC, Favreau P, Cheneval O, Laing GD, Wilkinson MC, Miller RL, Stöcklin R, Harrison RA. Wagstaff SC, et al. Among authors: wilkinson mc. Biochem Biophys Res Commun. 2008 Jan 25;365(4):650-6. doi: 10.1016/j.bbrc.2007.11.027. Epub 2007 Nov 20. Biochem Biophys Res Commun. 2008. PMID: 18029259

9

Snake Venom Metalloproteinases and Their Peptide Inhibitors from Myanmar Russell's Viper Venom.

Yee KT, Pitts M, Tongyoo P, Rojnuckarin P, Wilkinson MC. Yee KT, et al. Among authors: wilkinson mc. Toxins (Basel). 2016 Dec 30;9(1):15. doi: 10.3390/toxins9010015. Toxins (Basel). 2016. PMID: 28042812 Free PMC article.

10

Characterization of a novel protein from Proatheris superciliaris venom: proatherocytin, a 34-kDa platelet receptor PAR1 agonist.

Laing GD, Compton SJ, Ramachandran R, Fuller GL, Wilkinson MC, Wagstaff SC, Watson SP, Kamiguti AS, Theakston RD, Senis YA. Laing GD, et al. Among authors: wilkinson mc. Toxicon. 2005 Oct;46(5):490-9. doi: 10.1016/j.toxicon.2005.06.011. Toxicon. 2005. PMID: 16112700

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