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The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens.
Zhou N, Jiang Y, Bergquist TR, Lee AJ, Kacsoh BZ, Crocker AW, Lewis KA, Georghiou G, Nguyen HN, Hamid MN, Davis L, Dogan T, Atalay V, Rifaioglu AS, Dalkıran A, Cetin Atalay R, Zhang C, Hurto RL, Freddolino PL, Zhang Y, Bhat P, Supek F, Fernández JM, Gemovic B, Perovic VR, Davidović RS, Sumonja N, Veljkovic N, Asgari E, Mofrad MRK, Profiti G, Savojardo C, Martelli PL, Casadio R, Boecker F, Schoof H, Kahanda I, Thurlby N, McHardy AC, Renaux A, Saidi R, Gough J, Freitas AA, Antczak M, Fabris F, Wass MN, Hou J, Cheng J, Wang Z, Romero AE, Paccanaro A, Yang H, Goldberg T, Zhao C, Holm L, Törönen P, Medlar AJ, Zosa E, Borukhov I, Novikov I, Wilkins A, Lichtarge O, Chi PH, Tseng WC, Linial M, Rose PW, Dessimoz C, Vidulin V, Dzeroski S, Sillitoe I, Das S, Lees JG, Jones DT, Wan C, Cozzetto D, Fa R, Torres M, Warwick Vesztrocy A, Rodriguez JM, Tress ML, Frasca M, Notaro M, Grossi G, Petrini A, Re M, Valentini G, Mesiti M, Roche DB, Reeb J, Ritchie DW, Aridhi S, Alborzi SZ, Devignes MD, Koo DCE, Bonneau R, Gligorijević V, Barot M, Fang H, Toppo S, Lavezzo E, Falda M, Berselli M, Tosatto SCE, Carraro M, Piovesan D, Ur Rehman H, Mao Q, Zhang S, Vucetic S, Black GS, Jo D, Suh E, Dayton … See abstract for full author list ➔ Zhou N, et al. Among authors: wilkins a. Genome Biol. 2019 Nov 19;20(1):244. doi: 10.1186/s13059-019-1835-8. Genome Biol. 2019. PMID: 31744546 Free PMC article.
The use of evolutionary patterns in protein annotation.
Wilkins AD, Bachman BJ, Erdin S, Lichtarge O. Wilkins AD, et al. Curr Opin Struct Biol. 2012 Jun;22(3):316-25. doi: 10.1016/j.sbi.2012.05.001. Epub 2012 May 24. Curr Opin Struct Biol. 2012. PMID: 22633559 Free PMC article. Review.
Evolution: a guide to perturb protein function and networks.
Lichtarge O, Wilkins A. Lichtarge O, et al. Among authors: wilkins a. Curr Opin Struct Biol. 2010 Jun;20(3):351-9. doi: 10.1016/j.sbi.2010.04.002. Epub 2010 May 3. Curr Opin Struct Biol. 2010. PMID: 20444593 Free PMC article. Review.
Prediction and redesign of protein-protein interactions.
Lua RC, Marciano DC, Katsonis P, Adikesavan AK, Wilkins AD, Lichtarge O. Lua RC, et al. Prog Biophys Mol Biol. 2014 Nov-Dec;116(2-3):194-202. doi: 10.1016/j.pbiomolbio.2014.05.004. Epub 2014 May 27. Prog Biophys Mol Biol. 2014. PMID: 24878423 Free PMC article. Review.
718 results