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Suppression of costimulation by human cytomegalovirus promotes evasion of cellular immune defenses.
Wang ECY, Pjechova M, Nightingale K, Vlahava VM, Patel M, Ruckova E, Forbes SK, Nobre L, Antrobus R, Roberts D, Fielding CA, Seirafian S, Davies J, Murrell I, Lau B, Wilkie GS, Suárez NM, Stanton RJ, Vojtesek B, Davison A, Lehner PJ, Weekes MP, Wilkinson GWG, Tomasec P. Wang ECY, et al. Among authors: wilkie gs. Proc Natl Acad Sci U S A. 2018 May 8;115(19):4998-5003. doi: 10.1073/pnas.1720950115. Epub 2018 Apr 24. Proc Natl Acad Sci U S A. 2018. PMID: 29691324 Free PMC article.
HCMV pUL135 remodels the actin cytoskeleton to impair immune recognition of infected cells.
Stanton RJ, Prod'homme V, Purbhoo MA, Moore M, Aicheler RJ, Heinzmann M, Bailer SM, Haas J, Antrobus R, Weekes MP, Lehner PJ, Vojtesek B, Miners KL, Man S, Wilkie GS, Davison AJ, Wang ECY, Tomasec P, Wilkinson GWG. Stanton RJ, et al. Among authors: wilkie gs. Cell Host Microbe. 2014 Aug 13;16(2):201-214. doi: 10.1016/j.chom.2014.07.005. Cell Host Microbe. 2014. PMID: 25121749 Free PMC article.
Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141.
Hsu JL, van den Boomen DJ, Tomasec P, Weekes MP, Antrobus R, Stanton RJ, Ruckova E, Sugrue D, Wilkie GS, Davison AJ, Wilkinson GW, Lehner PJ. Hsu JL, et al. Among authors: wilkie gs. PLoS Pathog. 2015 Apr 14;11(4):e1004811. doi: 10.1371/journal.ppat.1004811. eCollection 2015 Apr. PLoS Pathog. 2015. PMID: 25875600 Free PMC article.
Human cytomegalovirus: taking the strain.
Wilkinson GW, Davison AJ, Tomasec P, Fielding CA, Aicheler R, Murrell I, Seirafian S, Wang EC, Weekes M, Lehner PJ, Wilkie GS, Stanton RJ. Wilkinson GW, et al. Among authors: wilkie gs. Med Microbiol Immunol. 2015 Jun;204(3):273-84. doi: 10.1007/s00430-015-0411-4. Epub 2015 Apr 17. Med Microbiol Immunol. 2015. PMID: 25894764 Free PMC article. Review.
Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation.
Fielding CA, Weekes MP, Nobre LV, Ruckova E, Wilkie GS, Paulo JA, Chang C, Suárez NM, Davies JA, Antrobus R, Stanton RJ, Aicheler RJ, Nichols H, Vojtesek B, Trowsdale J, Davison AJ, Gygi SP, Tomasec P, Lehner PJ, Wilkinson GW. Fielding CA, et al. Among authors: wilkie gs. Elife. 2017 Feb 10;6:e22206. doi: 10.7554/eLife.22206. Elife. 2017. PMID: 28186488 Free PMC article.
Characterization of Human Cytomegalovirus Genome Diversity in Immunocompromised Hosts by Whole-Genome Sequencing Directly From Clinical Specimens.
Hage E, Wilkie GS, Linnenweber-Held S, Dhingra A, Suárez NM, Schmidt JJ, Kay-Fedorov PC, Mischak-Weissinger E, Heim A, Schwarz A, Schulz TF, Davison AJ, Ganzenmueller T. Hage E, et al. Among authors: wilkie gs. J Infect Dis. 2017 Jun 1;215(11):1673-1683. doi: 10.1093/infdis/jix157. J Infect Dis. 2017. PMID: 28368496
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