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Decrypting drug actions and protein modifications by dose- and time-resolved proteomics.
Zecha J, Bayer FP, Wiechmann S, Woortman J, Berner N, Müller J, Schneider A, Kramer K, Abril-Gil M, Hopf T, Reichart L, Chen L, Hansen FM, Lechner S, Samaras P, Eckert S, Lautenbacher L, Reinecke M, Hamood F, Prokofeva P, Vornholz L, Falcomatà C, Dorsch M, Schröder A, Venhuizen A, Wilhelm S, Médard G, Stoehr G, Ruland J, Grüner BM, Saur D, Buchner M, Ruprecht B, Hahne H, The M, Wilhelm M, Kuster B. Zecha J, et al. Among authors: wilhelm m, wilhelm s. Science. 2023 Apr 7;380(6640):93-101. doi: 10.1126/science.ade3925. Epub 2023 Mar 16. Science. 2023. PMID: 36926954 Free PMC article.
Global proteome analysis of the NCI-60 cell line panel.
Gholami AM, Hahne H, Wu Z, Auer FJ, Meng C, Wilhelm M, Kuster B. Gholami AM, et al. Among authors: wilhelm m. Cell Rep. 2013 Aug 15;4(3):609-20. doi: 10.1016/j.celrep.2013.07.018. Epub 2013 Aug 8. Cell Rep. 2013. PMID: 23933261 Free article.
Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics.
Helm D, Vissers JP, Hughes CJ, Hahne H, Ruprecht B, Pachl F, Grzyb A, Richardson K, Wildgoose J, Maier SK, Marx H, Wilhelm M, Becher I, Lemeer S, Bantscheff M, Langridge JI, Kuster B. Helm D, et al. Among authors: wilhelm m. Mol Cell Proteomics. 2014 Dec;13(12):3709-15. doi: 10.1074/mcp.M114.041038. Epub 2014 Aug 8. Mol Cell Proteomics. 2014. PMID: 25106551 Free PMC article.
Optimized chemical proteomics assay for kinase inhibitor profiling.
Médard G, Pachl F, Ruprecht B, Klaeger S, Heinzlmeir S, Helm D, Qiao H, Ku X, Wilhelm M, Kuehne T, Wu Z, Dittmann A, Hopf C, Kramer K, Kuster B. Médard G, et al. Among authors: wilhelm m. J Proteome Res. 2015 Mar 6;14(3):1574-86. doi: 10.1021/pr5012608. Epub 2015 Feb 20. J Proteome Res. 2015. PMID: 25660469
Chemoproteomics-Aided Medicinal Chemistry for the Discovery of EPHA2 Inhibitors.
Heinzlmeir S, Lohse J, Treiber T, Kudlinzki D, Linhard V, Gande SL, Sreeramulu S, Saxena K, Liu X, Wilhelm M, Schwalbe H, Kuster B, Médard G. Heinzlmeir S, et al. Among authors: wilhelm m. ChemMedChem. 2017 Jun 21;12(12):999-1011. doi: 10.1002/cmdc.201700217. Epub 2017 Jun 12. ChemMedChem. 2017. PMID: 28544567
1,409 results