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The RNA chaperone, Hfq, controls two luxR-type regulators and plays a key role in pathogenesis and production of antibiotics in Serratia sp. ATCC 39006.
Environ Microbiol. 2011 Oct;13(10):2649-66. doi: 10.1111/j.1462-2920.2011.02532.x. Epub 2011 Aug 8.
Environ Microbiol. 2011.
PMID: 21824244
The stationary phase sigma factor, RpoS, regulates the production of a carbapenem antibiotic, a bioactive prodigiosin and virulence in the enterobacterial pathogen Serratia sp. ATCC 39006.
Wilf NM, Salmond GPC.
Wilf NM, et al.
Microbiology (Reading). 2012 Mar;158(Pt 3):648-658. doi: 10.1099/mic.0.055780-0. Epub 2011 Dec 22.
Microbiology (Reading). 2012.
PMID: 22194349
Free article.
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RNA-seq reveals the RNA binding proteins, Hfq and RsmA, play various roles in virulence, antibiotic production and genomic flux in Serratia sp. ATCC 39006.
Wilf NM, Reid AJ, Ramsay JP, Williamson NR, Croucher NJ, Gatto L, Hester SS, Goulding D, Barquist L, Lilley KS, Kingsley RA, Dougan G, Salmond GP.
Wilf NM, et al.
BMC Genomics. 2013 Nov 22;14(1):822. doi: 10.1186/1471-2164-14-822.
BMC Genomics. 2013.
PMID: 24267595
Free PMC article.
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Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles.
Fineran PC, Iglesias Cans MC, Ramsay JP, Wilf NM, Cossyleon D, McNeil MB, Williamson NR, Monson RE, Becher SA, Stanton JA, Brügger K, Brown SD, Salmond GP.
Fineran PC, et al. Among authors: wilf nm.
Genome Announc. 2013 Dec 12;1(6):e01039-13. doi: 10.1128/genomeA.01039-13.
Genome Announc. 2013.
PMID: 24336377
Free PMC article.
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SdhE is a conserved protein required for flavinylation of succinate dehydrogenase in bacteria.
McNeil MB, Clulow JS, Wilf NM, Salmond GP, Fineran PC.
McNeil MB, et al. Among authors: wilf nm.
J Biol Chem. 2012 May 25;287(22):18418-28. doi: 10.1074/jbc.M111.293803. Epub 2012 Apr 3.
J Biol Chem. 2012.
PMID: 22474332
Free PMC article.
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Effect of Hfq on RprA-rpoS mRNA pairing: Hfq-RNA binding and the influence of the 5' rpoS mRNA leader region.
Updegrove T, Wilf N, Sun X, Wartell RM.
Updegrove T, et al.
Biochemistry. 2008 Oct 28;47(43):11184-95. doi: 10.1021/bi800479p. Epub 2008 Oct 1.
Biochemistry. 2008.
PMID: 18826256
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Optimized orthogonal translation of unnatural amino acids enables spontaneous protein double-labelling and FRET.
Wang K, Sachdeva A, Cox DJ, Wilf NM, Lang K, Wallace S, Mehl RA, Chin JW.
Wang K, et al. Among authors: wilf nm.
Nat Chem. 2014 May;6(5):393-403. doi: 10.1038/nchem.1919. Epub 2014 Apr 20.
Nat Chem. 2014.
PMID: 24755590
Free PMC article.
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