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A BET Protein Inhibitor Targeting Mononuclear Myeloid Cells Affects Specific Inflammatory Mediators and Pathways in Crohn's Disease.
Elfiky AMI, Hageman IL, Becker MAJ, Verhoeff J, Li Yim AYF, Joustra VW, Mulders L, Fung I, Rioja I, Prinjha RK, Smithers NN, Furze RC, Mander PK, Bell MJ, Buskens CJ, D'Haens GR, Wildenberg ME, de Jonge WJ. Elfiky AMI, et al. Among authors: wildenberg me. Cells. 2022 Sep 12;11(18):2846. doi: 10.3390/cells11182846. Cells. 2022. PMID: 36139421 Free PMC article.
Development of Fibrosis in Acute and Longstanding Ulcerative Colitis.
de Bruyn JR, Meijer SL, Wildenberg ME, Bemelman WA, van den Brink GR, D'Haens GR. de Bruyn JR, et al. Among authors: wildenberg me. J Crohns Colitis. 2015 Nov;9(11):966-72. doi: 10.1093/ecco-jcc/jjv133. Epub 2015 Aug 5. J Crohns Colitis. 2015. PMID: 26245217
Autophagy Contributes to the Induction of Anti-TNF Induced Macrophages.
Levin AD, Koelink PJ, Bloemendaal FM, Vos AC, D'Haens GR, van den Brink GR, Wildenberg ME. Levin AD, et al. Among authors: wildenberg me. J Crohns Colitis. 2016 Mar;10(3):323-9. doi: 10.1093/ecco-jcc/jjv174. Epub 2015 Sep 27. J Crohns Colitis. 2016. PMID: 26417049 Free PMC article.
Fc Receptor-mediated Effector Function Contributes to the Therapeutic Response of Anti-TNF Monoclonal Antibodies in a Mouse Model of Inflammatory Bowel Disease.
McRae BL, Levin AD, Wildenberg ME, Koelink PJ, Bousquet P, Mikaelian I, Sterman AS, Bryant S, D'Haens G, Kamath R, Salfeld J, van den Brink GR. McRae BL, et al. Among authors: wildenberg me. J Crohns Colitis. 2016 Jan;10(1):69-76. doi: 10.1093/ecco-jcc/jjv179. Epub 2015 Oct 1. J Crohns Colitis. 2016. PMID: 26429698
miR-511-3p, embedded in the macrophage mannose receptor gene, contributes to intestinal inflammation.
Heinsbroek SE, Squadrito ML, Schilderink R, Hilbers FW, Verseijden C, Hofmann M, Helmke A, Boon L, Wildenberg ME, Roelofs JJ, Ponsioen CY, Peters CP, Te Velde AA, Gordon S, De Palma M, de Jonge WJ. Heinsbroek SE, et al. Among authors: wildenberg me. Mucosal Immunol. 2016 Jul;9(4):960-73. doi: 10.1038/mi.2015.113. Epub 2015 Nov 4. Mucosal Immunol. 2016. PMID: 26530135 Free article.
The ATG16L1 risk allele associated with Crohn's disease results in a Rac1-dependent defect in dendritic cell migration that is corrected by thiopurines.
Wildenberg ME, Koelink PJ, Diederen K, Te Velde AA, Wolfkamp SC, Nuij VJ, Peppelenbosch MP, Nobis M, Sansom OJ, Anderson KI, van der Woude CJ, D'Haens GR, van den Brink GR. Wildenberg ME, et al. Mucosal Immunol. 2017 Mar;10(2):352-360. doi: 10.1038/mi.2016.65. Epub 2016 Jul 20. Mucosal Immunol. 2017. PMID: 27435106 Free article.
The Future of Janus Kinase Inhibitors in Inflammatory Bowel Disease.
De Vries LCS, Wildenberg ME, De Jonge WJ, D'Haens GR. De Vries LCS, et al. Among authors: wildenberg me. J Crohns Colitis. 2017 Jul 1;11(7):885-893. doi: 10.1093/ecco-jcc/jjx003. J Crohns Colitis. 2017. PMID: 28158411 Free PMC article. Review.
The role of the mesentery in Crohn's disease.
Buskens CJ, de Groof EJ, Bemelman WA, Wildenberg ME. Buskens CJ, et al. Among authors: wildenberg me. Lancet Gastroenterol Hepatol. 2017 Apr;2(4):245-246. doi: 10.1016/S2468-1253(17)30049-3. Epub 2017 Mar 9. Lancet Gastroenterol Hepatol. 2017. PMID: 28404147 No abstract available.
Anti-Tumor Necrosis Factor With a Glyco-Engineered Fc-Region Has Increased Efficacy in Mice With Colitis.
Bloemendaal FM, Levin AD, Wildenberg ME, Koelink PJ, McRae BL, Salfeld J, Lum J, van der Neut Kolfschoten M, Claassens JW, Visser R, Bentlage A, D'Haens GRAM, Verbeek JS, Vidarsson G, van den Brink GR. Bloemendaal FM, et al. Among authors: wildenberg me. Gastroenterology. 2017 Nov;153(5):1351-1362.e4. doi: 10.1053/j.gastro.2017.07.021. Epub 2017 Jul 27. Gastroenterology. 2017. PMID: 28756234
89 results