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Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways.
Syu LJ, Zhao X, Zhang Y, Grachtchouk M, Demitrack E, Ermilov A, Wilbert DM, Zheng X, Kaatz A, Greenson JK, Gumucio DL, Merchant JL, di Magliano MP, Samuelson LC, Dlugosz AA. Syu LJ, et al. Among authors: wilbert dm. Oncotarget. 2016 Mar 1;7(9):10255-70. doi: 10.18632/oncotarget.7182. Oncotarget. 2016. PMID: 26859571 Free PMC article.
Direct cellular reprogramming enables development of viral T antigen-driven Merkel cell carcinoma in mice.
Verhaegen ME, Harms PW, Van Goor JJ, Arche J, Patrick MT, Wilbert D, Zabawa H, Grachtchouk M, Liu CJ, Hu K, Kelly MC, Chen P, Saunders TL, Weidinger S, Syu LJ, Runge JS, Gudjonsson JE, Wong SY, Brownell I, Cieslik M, Udager AM, Chinnaiyan AM, Tsoi LC, Dlugosz AA. Verhaegen ME, et al. Among authors: wilbert d. J Clin Invest. 2022 Apr 1;132(7):e152069. doi: 10.1172/JCI152069. J Clin Invest. 2022. PMID: 35143422 Free PMC article.
Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.
Verhaegen ME, Mangelberger D, Harms PW, Vozheiko TD, Weick JW, Wilbert DM, Saunders TL, Ermilov AN, Bichakjian CK, Johnson TM, Imperiale MJ, Dlugosz AA. Verhaegen ME, et al. Among authors: wilbert dm. J Invest Dermatol. 2015 May;135(5):1415-1424. doi: 10.1038/jid.2014.446. Epub 2014 Oct 14. J Invest Dermatol. 2015. PMID: 25313532 Free PMC article.
Transgenic expression of interferon-γ in mouse stomach leads to inflammation, metaplasia, and dysplasia.
Syu LJ, El-Zaatari M, Eaton KA, Liu Z, Tetarbe M, Keeley TM, Pero J, Ferris J, Wilbert D, Kaatz A, Zheng X, Qiao X, Grachtchouk M, Gumucio DL, Merchant JL, Samuelson LC, Dlugosz AA. Syu LJ, et al. Among authors: wilbert d. Am J Pathol. 2012 Dec;181(6):2114-25. doi: 10.1016/j.ajpath.2012.08.017. Epub 2012 Oct 1. Am J Pathol. 2012. PMID: 23036899 Free PMC article.
67 results