Wijtmans M - Search Results

1

Modulators of CXCR4 and CXCR7/ACKR3 Function.

Adlere I, Caspar B, Arimont M, Dekkers S, Visser K, Stuijt J, de Graaf C, Stocks M, Kellam B, Briddon S, Wijtmans M, de Esch I, Hill S, Leurs R. Adlere I, et al. Among authors: wijtmans m. Mol Pharmacol. 2019 Dec;96(6):737-752. doi: 10.1124/mol.119.117663. Epub 2019 Sep 23. Mol Pharmacol. 2019. PMID: 31548340 Review.

2

Keynote review: histamine H3 receptor antagonists reach out for the clinic.

Celanire S, Wijtmans M, Talaga P, Leurs R, de Esch IJ. Celanire S, et al. Among authors: wijtmans m. Drug Discov Today. 2005 Dec;10(23-24):1613-27. doi: 10.1016/S1359-6446(05)03625-1. Drug Discov Today. 2005. PMID: 16376822 Review.

3

Chemical insights in the concept of hybrid drugs: the antitumor effect of nitric oxide-donating aspirin involves a quinone methide but not nitric oxide nor aspirin.

Hulsman N, Medema JP, Bos C, Jongejan A, Leurs R, Smit MJ, de Esch IJ, Richel D, Wijtmans M. Hulsman N, et al. Among authors: wijtmans m. J Med Chem. 2007 May 17;50(10):2424-31. doi: 10.1021/jm061371e. Epub 2007 Apr 19. J Med Chem. 2007. PMID: 17441704

4

Histamine H3 receptor ligands break ground in a remarkable plethora of therapeutic areas.

Wijtmans M, Leurs R, de Esch I. Wijtmans M, et al. Expert Opin Investig Drugs. 2007 Jul;16(7):967-85. doi: 10.1517/13543784.16.7.967. Expert Opin Investig Drugs. 2007. PMID: 17594183 Review.

5

4-benzyl-1H-imidazoles with oxazoline termini as histamine H3 receptor agonists.

Wijtmans M, Celanire S, Snip E, Gillard MR, Gelens E, Collart PP, Venhuis BJ, Christophe B, Hulscher S, van der Goot H, Lebon F, Timmerman H, Bakker RA, Lallemand BI, Leurs R, Talaga PE, de Esch IJ. Wijtmans M, et al. J Med Chem. 2008 May 22;51(10):2944-53. doi: 10.1021/jm7014149. Epub 2008 Apr 24. J Med Chem. 2008. PMID: 18433114

6

Towards small-molecule CXCR3 ligands with clinical potential.

Wijtmans M, Verzijl D, Leurs R, de Esch IJ, Smit MJ. Wijtmans M, et al. ChemMedChem. 2008 Jun;3(6):861-72. doi: 10.1002/cmdc.200700365. ChemMedChem. 2008. PMID: 18442035 Review.

7

Exploring a pocket for polycycloaliphatic groups in the CXCR3 receptor with the aid of a modular synthetic strategy.

Wijtmans M, Verzijl D, van Dam CM, Bosch L, Smit MJ, Leurs R, de Esch IJ. Wijtmans M, et al. Bioorg Med Chem Lett. 2009 Apr 15;19(8):2252-7. doi: 10.1016/j.bmcl.2009.02.093. Epub 2009 Feb 27. Bioorg Med Chem Lett. 2009. PMID: 19299127

8

Development of a selective ESI-MS derivatization reagent: synthesis and optimization for the analysis of aldehydes in biological mixtures.

Eggink M, Wijtmans M, Ekkebus R, Lingeman H, de Esch IJ, Kool J, Niessen WM, Irth H. Eggink M, et al. Among authors: wijtmans m. Anal Chem. 2008 Dec 1;80(23):9042-51. doi: 10.1021/ac801429w. Anal Chem. 2008. PMID: 19551932

9

Targeted LC-MS derivatization for aldehydes and carboxylic acids with a new derivatization agent 4-APEBA.

Eggink M, Wijtmans M, Kretschmer A, Kool J, Lingeman H, de Esch IJ, Niessen WM, Irth H. Eggink M, et al. Among authors: wijtmans m. Anal Bioanal Chem. 2010 May;397(2):665-75. doi: 10.1007/s00216-010-3575-1. Epub 2010 Mar 19. Anal Bioanal Chem. 2010. PMID: 20238107 Free PMC article.

10

Online fluorescence enhancement assay for the acetylcholine binding protein with parallel mass spectrometric identification.

Kool J, de Kloe GE, Bruyneel B, de Vlieger JS, Retra K, Wijtmans M, van Elk R, Smit AB, Leurs R, Lingeman H, de Esch IJ, Irth H. Kool J, et al. Among authors: wijtmans m. J Med Chem. 2010 Jun 24;53(12):4720-30. doi: 10.1021/jm100230k. J Med Chem. 2010. PMID: 20518527

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