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The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation.
Gatsiou A, Tual-Chalot S, Napoli M, Ortega-Gomez A, Regen T, Badolia R, Cesarini V, Garcia-Gonzalez C, Chevre R, Ciliberti G, Silvestre-Roig C, Martini M, Hoffmann J, Hamouche R, Visker JR, Diakos N, Wietelmann A, Silvestris DA, Georgiopoulos G, Moshfegh A, Schneider A, Chen W, Guenther S, Backs J, Kwak S, Selzman CH, Stamatelopoulos K, Rose-John S, Trautwein C, Spyridopoulos I, Braun T, Waisman A, Gallo A, Drakos SG, Dimmeler S, Sperandio M, Soehnlein O, Stellos K. Gatsiou A, et al. Among authors: wietelmann a. Immunity. 2023 May 9;56(5):979-997.e11. doi: 10.1016/j.immuni.2023.03.021. Epub 2023 Apr 25. Immunity. 2023. PMID: 37100060 Free article.
Digenic inheritance of mutations in EPHA2 and SLC26A4 in Pendred syndrome.
Li M, Nishio SY, Naruse C, Riddell M, Sapski S, Katsuno T, Hikita T, Mizapourshafiyi F, Smith FM, Cooper LT, Lee MG, Asano M, Boettger T, Krueger M, Wietelmann A, Graumann J, Day BW, Boyd AW, Offermanns S, Kitajiri SI, Usami SI, Nakayama M. Li M, et al. Among authors: wietelmann a. Nat Commun. 2020 Mar 12;11(1):1343. doi: 10.1038/s41467-020-15198-9. Nat Commun. 2020. PMID: 32165640 Free PMC article.
Sham surgery and inter-individual heterogeneity are major determinants of monocyte subset kinetics in a mouse model of myocardial infarction.
Hoffmann J, Ospelt M, Troidl C, Voss S, Liebetrau C, Kim WK, Rolf A, Wietelmann A, Braun T, Troidl K, Sadayappan S, Barefield D, Hamm C, Nef H, Möllmann H. Hoffmann J, et al. Among authors: wietelmann a. PLoS One. 2014 Jun 3;9(6):e98456. doi: 10.1371/journal.pone.0098456. eCollection 2014. PLoS One. 2014. PMID: 24893162 Free PMC article.
Myostatin induces interstitial fibrosis in the heart via TAK1 and p38.
Biesemann N, Mendler L, Kostin S, Wietelmann A, Borchardt T, Braun T. Biesemann N, et al. Among authors: wietelmann a. Cell Tissue Res. 2015 Sep;361(3):779-87. doi: 10.1007/s00441-015-2139-2. Epub 2015 Mar 1. Cell Tissue Res. 2015. PMID: 25725788
ADAR1 Prevents Autoinflammatory Processes in the Heart Mediated by IRF7.
Garcia-Gonzalez C, Dieterich C, Maroli G, Wiesnet M, Wietelmann A, Li X, Yuan X, Graumann J, Stellos K, Kubin T, Schneider A, Braun T. Garcia-Gonzalez C, et al. Among authors: wietelmann a. Circ Res. 2022 Sep 16;131(7):580-597. doi: 10.1161/CIRCRESAHA.122.320839. Epub 2022 Aug 24. Circ Res. 2022. PMID: 36000401 Free article.
Oncostatin M is a major mediator of cardiomyocyte dedifferentiation and remodeling.
Kubin T, Pöling J, Kostin S, Gajawada P, Hein S, Rees W, Wietelmann A, Tanaka M, Lörchner H, Schimanski S, Szibor M, Warnecke H, Braun T. Kubin T, et al. Among authors: wietelmann a. Cell Stem Cell. 2011 Nov 4;9(5):420-32. doi: 10.1016/j.stem.2011.08.013. Cell Stem Cell. 2011. PMID: 22056139 Free article.
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