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Targeting Wnt-ß-Catenin-FOSL Signaling Ameliorates Right Ventricular Remodeling.
Nayakanti SR, Friedrich A, Sarode P, Jafari L, Maroli G, Boehm M, Bourgeois A, Grobs Y, Khassafi F, Kuenne C, Guenther S, Dabral S, Wilhelm J, Weiss A, Wietelmann A, Kojonazarov B, Janssen W, Looso M, de Man F, Provencher S, Tello K, Seeger W, Bonnet S, Savai R, Schermuly RT, Pullamsetti SS. Nayakanti SR, et al. Among authors: wietelmann a. Circ Res. 2023 May 26;132(11):1468-1485. doi: 10.1161/CIRCRESAHA.122.321725. Epub 2023 Apr 12. Circ Res. 2023. PMID: 37042252
Sirt7 promotes adipogenesis in the mouse by inhibiting autocatalytic activation of Sirt1.
Fang J, Ianni A, Smolka C, Vakhrusheva O, Nolte H, Krüger M, Wietelmann A, Simonet NG, Adrian-Segarra JM, Vaquero A, Braun T, Bober E. Fang J, et al. Among authors: wietelmann a. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8352-E8361. doi: 10.1073/pnas.1706945114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923965 Free PMC article.
Deletion of Fn14 receptor protects from right heart fibrosis and dysfunction.
Novoyatleva T, Schymura Y, Janssen W, Strobl F, Swiercz JM, Patra C, Posern G, Wietelmann A, Zheng TS, Schermuly RT, Engel FB. Novoyatleva T, et al. Among authors: wietelmann a. Basic Res Cardiol. 2013 Mar;108(2):325. doi: 10.1007/s00395-012-0325-x. Epub 2013 Jan 17. Basic Res Cardiol. 2013. PMID: 23325387 Free PMC article.
TWEAK/Fn14 axis is a positive regulator of cardiac hypertrophy.
Novoyatleva T, Janssen W, Wietelmann A, Schermuly RT, Engel FB. Novoyatleva T, et al. Among authors: wietelmann a. Cytokine. 2013 Oct;64(1):43-5. doi: 10.1016/j.cyto.2013.05.009. Epub 2013 Jun 10. Cytokine. 2013. PMID: 23764551
5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure.
Janssen W, Schymura Y, Novoyatleva T, Kojonazarov B, Boehm M, Wietelmann A, Luitel H, Murmann K, Krompiec DR, Tretyn A, Pullamsetti SS, Weissmann N, Seeger W, Ghofrani HA, Schermuly RT. Janssen W, et al. Among authors: wietelmann a. Biomed Res Int. 2015;2015:438403. doi: 10.1155/2015/438403. Epub 2015 Feb 1. Biomed Res Int. 2015. PMID: 25667920 Free PMC article.
46 results