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Mitochondrial membrane proteins and VPS35 orchestrate selective removal of mtDNA.
Sen A, Kallabis S, Gaedke F, Jüngst C, Boix J, Nüchel J, Maliphol K, Hofmann J, Schauss AC, Krüger M, Wiesner RJ, Pla-Martín D. Sen A, et al. Among authors: wiesner rj. Nat Commun. 2022 Nov 7;13(1):6704. doi: 10.1038/s41467-022-34205-9. Nat Commun. 2022. PMID: 36344526 Free PMC article.
Negative regulation of mitochondrial transcription by mitochondrial topoisomerase I.
Sobek S, Dalla Rosa I, Pommier Y, Bornholz B, Kalfalah F, Zhang H, Wiesner RJ, von Kleist-Retzow JC, Hillebrand F, Schaal H, Mielke C, Christensen MO, Boege F. Sobek S, et al. Among authors: wiesner rj. Nucleic Acids Res. 2013 Nov;41(21):9848-57. doi: 10.1093/nar/gkt768. Epub 2013 Aug 27. Nucleic Acids Res. 2013. PMID: 23982517 Free PMC article.
FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders.
Lehtonen JM, Forsström S, Bottani E, Viscomi C, Baris OR, Isoniemi H, Höckerstedt K, Österlund P, Hurme M, Jylhävä J, Leppä S, Markkula R, Heliö T, Mombelli G, Uusimaa J, Laaksonen R, Laaksovirta H, Auranen M, Zeviani M, Smeitink J, Wiesner RJ, Nakada K, Isohanni P, Suomalainen A. Lehtonen JM, et al. Among authors: wiesner rj. Neurology. 2016 Nov 29;87(22):2290-2299. doi: 10.1212/WNL.0000000000003374. Epub 2016 Oct 28. Neurology. 2016. PMID: 27794108 Free PMC article.
CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels.
Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A. Szczepanowska K, et al. Among authors: wiesner rj. EMBO J. 2016 Dec 1;35(23):2566-2583. doi: 10.15252/embj.201694253. Epub 2016 Oct 20. EMBO J. 2016. PMID: 27797820 Free PMC article.
Reshaping membranes to build mitochondrial DNA.
Pla-Martin D, Wiesner RJ. Pla-Martin D, et al. Among authors: wiesner rj. PLoS Genet. 2019 Jun 6;15(6):e1008140. doi: 10.1371/journal.pgen.1008140. eCollection 2019 Jun. PLoS Genet. 2019. PMID: 31170157 Free PMC article. No abstract available.
111 results