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Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila.
Bjedov I, Cochemé HM, Foley A, Wieser D, Woodling NS, Castillo-Quan JI, Norvaisas P, Lujan C, Regan JC, Toivonen JM, Murphy MP, Thornton J, Kinghorn KJ, Neufeld TP, Cabreiro F, Partridge L. Bjedov I, et al. Among authors: wieser d. PLoS Genet. 2020 Nov 30;16(11):e1009083. doi: 10.1371/journal.pgen.1009083. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33253201 Free PMC article.
Antimalarial Activity of KAF156 in Falciparum and Vivax Malaria.
White NJ, Duong TT, Uthaisin C, Nosten F, Phyo AP, Hanboonkunupakarn B, Pukrittayakamee S, Jittamala P, Chuthasmit K, Cheung MS, Feng Y, Li R, Magnusson B, Sultan M, Wieser D, Xun X, Zhao R, Diagana TT, Pertel P, Leong FJ. White NJ, et al. Among authors: wieser d. N Engl J Med. 2016 Sep 22;375(12):1152-60. doi: 10.1056/NEJMoa1602250. N Engl J Med. 2016. PMID: 27653565 Free PMC article. Clinical Trial.
Nuclear hormone receptor DHR96 mediates the resistance to xenobiotics but not the increased lifespan of insulin-mutant Drosophila.
Afschar S, Toivonen JM, Hoffmann JM, Tain LS, Wieser D, Finlayson AJ, Driege Y, Alic N, Emran S, Stinn J, Froehlich J, Piper MD, Partridge L. Afschar S, et al. Among authors: wieser d. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1321-6. doi: 10.1073/pnas.1515137113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787908 Free PMC article.
Computational biology for ageing.
Wieser D, Papatheodorou I, Ziehm M, Thornton JM. Wieser D, et al. Philos Trans R Soc Lond B Biol Sci. 2011 Jan 12;366(1561):51-63. doi: 10.1098/rstb.2010.0286. Philos Trans R Soc Lond B Biol Sci. 2011. PMID: 21115530 Free PMC article. Review.
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span.
Selman C, Tullet JM, Wieser D, Irvine E, Lingard SJ, Choudhury AI, Claret M, Al-Qassab H, Carmignac D, Ramadani F, Woods A, Robinson IC, Schuster E, Batterham RL, Kozma SC, Thomas G, Carling D, Okkenhaug K, Thornton JM, Partridge L, Gems D, Withers DJ. Selman C, et al. Among authors: wieser d. Science. 2009 Oct 2;326(5949):140-4. doi: 10.1126/science.1177221. Science. 2009. PMID: 19797661 Free PMC article.
40 results