Wienk H - Search Results

1

A natural-product switch for a dynamic protein interface.

Scheepstra M, Nieto L, Hirsch AK, Fuchs S, Leysen S, Lam CV, in het Panhuis L, van Boeckel CA, Wienk H, Boelens R, Ottmann C, Milroy LG, Brunsveld L. Scheepstra M, et al. Among authors: wienk h. Angew Chem Int Ed Engl. 2014 Jun 16;53(25):6443-8. doi: 10.1002/anie.201403773. Epub 2014 May 12. Angew Chem Int Ed Engl. 2014. PMID: 24821627

2

Structural dynamics in the activation of Epac.

Harper SM, Wienk H, Wechselberger RW, Bos JL, Boelens R, Rehmann H. Harper SM, et al. Among authors: wienk h. J Biol Chem. 2008 Mar 7;283(10):6501-8. doi: 10.1074/jbc.M707849200. Epub 2007 Dec 31. J Biol Chem. 2008. PMID: 18167352 Free article.

3

E2-c-Cbl recognition is necessary but not sufficient for ubiquitination activity.

Huang A, de Jong RN, Wienk H, Winkler GS, Timmers HT, Boelens R. Huang A, et al. Among authors: wienk h. J Mol Biol. 2009 Jan 16;385(2):507-19. doi: 10.1016/j.jmb.2008.10.044. Epub 2008 Nov 1. J Mol Biol. 2009. PMID: 18996392

4

Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes.

Romanuka J, Folkers GE, Biris N, Tishchenko E, Wienk H, Bonvin AM, Kaptein R, Boelens R. Romanuka J, et al. Among authors: wienk h. J Mol Biol. 2009 Jul 17;390(3):478-89. doi: 10.1016/j.jmb.2009.05.022. Epub 2009 May 18. J Mol Biol. 2009. PMID: 19450607

5

Crystal structure and collagen-binding site of immune inhibitory receptor LAIR-1: unexpected implications for collagen binding by platelet receptor GPVI.

Brondijk TH, de Ruiter T, Ballering J, Wienk H, Lebbink RJ, van Ingen H, Boelens R, Farndale RW, Meyaard L, Huizinga EG. Brondijk TH, et al. Among authors: wienk h. Blood. 2010 Feb 18;115(7):1364-73. doi: 10.1182/blood-2009-10-246322. Epub 2009 Dec 10. Blood. 2010. PMID: 20007810 Free article.

6

¹H, ¹³C and ¹⁵N resonance assignments of wild-type Bacillus subtilis Lipase A and its mutant evolved towards thermostability.

Augustyniak W, Wienk H, Boelens R, Reetz MT. Augustyniak W, et al. Among authors: wienk h. Biomol NMR Assign. 2013 Oct;7(2):249-52. doi: 10.1007/s12104-012-9420-z. Epub 2012 Sep 21. Biomol NMR Assign. 2013. PMID: 22996591

7

The Fanconi anemia associated protein FAAP24 uses two substrate specific binding surfaces for DNA recognition.

Wienk H, Slootweg JC, Speerstra S, Kaptein R, Boelens R, Folkers GE. Wienk H, et al. Nucleic Acids Res. 2013 Jul;41(13):6739-49. doi: 10.1093/nar/gkt354. Epub 2013 May 9. Nucleic Acids Res. 2013. PMID: 23661679 Free PMC article.

8

The basic helix-loop-helix region of the transcriptional repressor hairy and enhancer of split 1 is preorganized to bind DNA.

Popovic M, Wienk H, Coglievina M, Boelens R, Pongor S, Pintar A. Popovic M, et al. Among authors: wienk h. Proteins. 2014 Apr;82(4):537-45. doi: 10.1002/prot.24507. Epub 2014 Jan 25. Proteins. 2014. PMID: 24403087

9

Binding hotspots of BAZ2B bromodomain: Histone interaction revealed by solution NMR driven docking.

Ferguson FM, Dias DM, Rodrigues JP, Wienk H, Boelens R, Bonvin AM, Abell C, Ciulli A. Ferguson FM, et al. Among authors: wienk h. Biochemistry. 2014 Oct 28;53(42):6706-16. doi: 10.1021/bi500909d. Epub 2014 Oct 15. Biochemistry. 2014. PMID: 25266743 Free PMC article.

10

The Cerebro-oculo-facio-skeletal Syndrome Point Mutation F231L in the ERCC1 DNA Repair Protein Causes Dissociation of the ERCC1-XPF Complex.

Faridounnia M, Wienk H, Kovačič L, Folkers GE, Jaspers NG, Kaptein R, Hoeijmakers JH, Boelens R. Faridounnia M, et al. Among authors: wienk h. J Biol Chem. 2015 Aug 14;290(33):20541-55. doi: 10.1074/jbc.M114.635169. Epub 2015 Jun 17. J Biol Chem. 2015. PMID: 26085086 Free PMC article.

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