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α-Amino bisphosphonate triazoles serve as GGDPS inhibitors.
Gehrke NR, Feng D, Ayub Ali M, Maalouf MA, Holstein SA, Wiemer DF. Gehrke NR, et al. Among authors: wiemer df. Bioorg Med Chem Lett. 2024 Apr 1;102:129659. doi: 10.1016/j.bmcl.2024.129659. Epub 2024 Feb 17. Bioorg Med Chem Lett. 2024. PMID: 38373465
Triazole-based inhibitors of geranylgeranyltransferase II.
Zhou X, Hartman SV, Born EJ, Smits JP, Holstein SA, Wiemer DF. Zhou X, et al. Among authors: wiemer df. Bioorg Med Chem Lett. 2013 Feb 1;23(3):764-6. doi: 10.1016/j.bmcl.2012.11.089. Epub 2012 Dec 1. Bioorg Med Chem Lett. 2013. PMID: 23266123 Free PMC article.
A new motif for inhibitors of geranylgeranyl diphosphate synthase.
Foust BJ, Allen C, Holstein SA, Wiemer DF. Foust BJ, et al. Among authors: wiemer df. Bioorg Med Chem. 2016 Aug 15;24(16):3734-41. doi: 10.1016/j.bmc.2016.06.019. Epub 2016 Jun 10. Bioorg Med Chem. 2016. PMID: 27338660 Free PMC article.
ω-Hydroxy isoprenoid bisphosphonates as linkable GGDPS inhibitors.
Bhuiyan NH, Varney ML, Bhattacharya DS, Payne WM, Mohs AM, Holstein SA, Wiemer DF. Bhuiyan NH, et al. Among authors: wiemer df. Bioorg Med Chem Lett. 2019 Oct 1;29(19):126633. doi: 10.1016/j.bmcl.2019.126633. Epub 2019 Aug 20. Bioorg Med Chem Lett. 2019. PMID: 31474482 Free PMC article.
126 results