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Genetic Engineering and Enrichment of Human NK Cells for CAR-Enhanced Immunotherapy of Hematological Malignancies.
Soldierer M, Bister A, Haist C, Thivakaran A, Cengiz SC, Sendker S, Bartels N, Thomitzek A, Smorra D, Hejazi M, Uhrberg M, Scheckenbach K, Monzel C, Wiek C, Reinhardt D, Niktoreh N, Hanenberg H. Soldierer M, et al. Among authors: wiek c. Front Immunol. 2022 Apr 7;13:847008. doi: 10.3389/fimmu.2022.847008. eCollection 2022. Front Immunol. 2022. PMID: 35464442 Free PMC article.
Adaptation of topoisomerase I paralogs to nuclear and mitochondrial DNA.
Dalla Rosa I, Goffart S, Wurm M, Wiek C, Essmann F, Sobek S, Schroeder P, Zhang H, Krutmann J, Hanenberg H, Schulze-Osthoff K, Mielke C, Pommier Y, Boege F, Christensen MO. Dalla Rosa I, et al. Among authors: wiek c. Nucleic Acids Res. 2009 Oct;37(19):6414-28. doi: 10.1093/nar/gkp708. Epub 2009 Aug 31. Nucleic Acids Res. 2009. PMID: 19720733 Free PMC article.
A natural tapasin isoform lacking exon 3 modifies peptide loading complex function.
Beutler N, Hauka S, Niepel A, Kowalewski DJ, Uhlmann J, Ghanem E, Erkelenz S, Wiek C, Hanenberg H, Schaal H, Stevanović S, Springer S, Momburg F, Hengel H, Halenius A. Beutler N, et al. Among authors: wiek c. Eur J Immunol. 2013 Jun;43(6):1459-69. doi: 10.1002/eji.201242725. Epub 2013 May 10. Eur J Immunol. 2013. PMID: 23519916 Free article.
AluY-mediated germline deletion, duplication and somatic stem cell reversion in UBE2T defines a new subtype of Fanconi anemia.
Virts EL, Jankowska A, Mackay C, Glaas MF, Wiek C, Kelich SL, Lottmann N, Kennedy FM, Marchal C, Lehnert E, Scharf RE, Dufour C, Lanciotti M, Farruggia P, Santoro A, Savasan S, Scheckenbach K, Schipper J, Wagenmann M, Lewis T, Leffak M, Farlow JL, Foroud TM, Honisch E, Niederacher D, Chakraborty SC, Vance GH, Pruss D, Timms KM, Lanchbury JS, Alpi AF, Hanenberg H. Virts EL, et al. Among authors: wiek c. Hum Mol Genet. 2015 Sep 15;24(18):5093-108. doi: 10.1093/hmg/ddv227. Epub 2015 Jun 17. Hum Mol Genet. 2015. PMID: 26085575 Free PMC article.
Optimized human CYP4B1 in combination with the alkylator prodrug 4-ipomeanol serves as a novel suicide gene system for adoptive T-cell therapies.
Roellecke K, Virts EL, Einholz R, Edson KZ, Altvater B, Rossig C, von Laer D, Scheckenbach K, Wagenmann M, Reinhardt D, Kramm CM, Rettie AE, Wiek C, Hanenberg H. Roellecke K, et al. Among authors: wiek c. Gene Ther. 2016 Jul;23(7):615-26. doi: 10.1038/gt.2016.38. Epub 2016 May 19. Gene Ther. 2016. PMID: 27092941
63 results