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Galectin-1 induces a tumor-associated macrophage phenotype and upregulates indoleamine 2,3-dioxygenase-1.
iScience. 2023 May 27;26(7):106984. doi: 10.1016/j.isci.2023.106984. eCollection 2023 Jul 21.
iScience. 2023.
PMID: 37534161
Free PMC article.
Osteoarthritis-Related Inflammation Blocks TGF-β's Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region.
Thielen N, Neefjes M, Wiegertjes R, van den Akker G, Vitters E, van Beuningen H, Blaney Davidson E, Koenders M, van Lent P, van de Loo F, van Caam A, van der Kraan P.
Thielen N, et al. Among authors: wiegertjes r.
Int J Mol Sci. 2021 Jul 29;22(15):8124. doi: 10.3390/ijms22158124.
Int J Mol Sci. 2021.
PMID: 34360888
Free PMC article.
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Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-β-mediated IL-6 receptor suppression.
Wiegertjes R, Thielen NGM, van Caam APM, van Laar M, van Beuningen HM, Koenders MI, van Lent PLEM, van der Kraan PM, van de Loo FAJ, Blaney Davidson EN.
Wiegertjes R, et al.
Osteoarthritis Cartilage. 2021 May;29(5):773-782. doi: 10.1016/j.joca.2021.01.008. Epub 2021 Feb 20.
Osteoarthritis Cartilage. 2021.
PMID: 33617971
Free article.
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A roadmap to target interleukin-6 in osteoarthritis.
Wiegertjes R, van de Loo FAJ, Blaney Davidson EN.
Wiegertjes R, et al.
Rheumatology (Oxford). 2020 Oct 1;59(10):2681-2694. doi: 10.1093/rheumatology/keaa248.
Rheumatology (Oxford). 2020.
PMID: 32691066
Free PMC article.
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TGF-β dampens IL-6 signaling in articular chondrocytes by decreasing IL-6 receptor expression.
Wiegertjes R, van Caam A, van Beuningen H, Koenders M, van Lent P, van der Kraan P, van de Loo F, Blaney Davidson E.
Wiegertjes R, et al.
Osteoarthritis Cartilage. 2019 Aug;27(8):1197-1207. doi: 10.1016/j.joca.2019.04.014. Epub 2019 May 2.
Osteoarthritis Cartilage. 2019.
PMID: 31054955
Free article.
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A three-dimensional model to study human synovial pathology.
Broeren MGA, Waterborg CEJ, Wiegertjes R, Thurlings RM, Koenders MI, Van Lent PLEM, Van der Kraan PM, Van de Loo FAJ.
Broeren MGA, et al. Among authors: wiegertjes r.
ALTEX. 2019;36(1):18-28. doi: 10.14573/altex.1804161. Epub 2018 Oct 9.
ALTEX. 2019.
PMID: 30303512
Free article.
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LPS-Stimulated Whole Blood Cytokine Production Is Not Related to Disease Behavior in Patients with Quiescent Crohn's Disease.
Broekman MM, Roelofs HM, Hoentjen F, Wiegertjes R, Stoel N, Joosten LA, de Jong DJ, Wanten GJ.
Broekman MM, et al. Among authors: wiegertjes r.
PLoS One. 2015 Jul 24;10(7):e0133932. doi: 10.1371/journal.pone.0133932. eCollection 2015.
PLoS One. 2015.
PMID: 26208333
Free PMC article.
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