Coordinated activation of mitochondrial respiration and exocytosis mediated by PKC signaling in pancreatic β cells.
Santo-Domingo J, Chareyron I, Dayon L, Núñez Galindo A, Cominetti O, Pilar Giner Giménez M, De Marchi U, Canto C, Kussmann M, Wiederkehr A.
Santo-Domingo J, et al. Among authors: wiederkehr a.
FASEB J. 2017 Mar;31(3):1028-1045. doi: 10.1096/fj.201600837R. Epub 2016 Dec 7.
FASEB J. 2017.
PMID: 27927723
Interactome analysis identified PKC, C-Raf, and ERK1/2 as the central phosphointeraction cluster. Prevention of ERK1/2 signaling by using a MEK1 inhibitor caused a marked decreased in phorbol 12-myristate 13-acetate-induced mitochondrial respiration. ...We conclude …
Interactome analysis identified PKC, C-Raf, and ERK1/2 as the central phosphointeraction cluster. Prevention of ERK1/2 signaling by using …