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Structure-Based Discovery of High-Affinity Small Molecule Ligands and Development of Tool Probes to Study the Role of Chitinase-3-Like Protein 1.
Czestkowski W, Krzemiński Ł, Piotrowicz MC, Mazur M, Pluta E, Andryianau G, Koralewski R, Matyszewski K, Olejniczak S, Kowalski M, Lisiecka K, Kozieł R, Piwowar K, Papiernik D, Nowotny M, Napiórkowska-Gromadzka A, Nowak E, Niedziałek D, Wieczorek G, Siwińska A, Rejczak T, Jędrzejczak K, Mulewski K, Olczak J, Zasłona Z, Gołębiowski A, Drzewicka K, Bartoszewicz A. Czestkowski W, et al. Among authors: wieczorek g. J Med Chem. 2024 Mar 14;67(5):3959-3985. doi: 10.1021/acs.jmedchem.3c02255. Epub 2024 Mar 1. J Med Chem. 2024. PMID: 38427954
Novel orally bioavailable piperidine derivatives as extracellular arginase inhibitors developed by a ring expansion.
Gzik A, Borek B, Chrzanowski J, Jedrzejczak K, Dziegielewski M, Brzezinska J, Nowicka J, Grzybowski MM, Rejczak T, Niedzialek D, Wieczorek G, Olczak J, Golebiowski A, Zaslona Z, Blaszczyk R. Gzik A, et al. Among authors: wieczorek g. Eur J Med Chem. 2024 Jan 15;264:116033. doi: 10.1016/j.ejmech.2023.116033. Epub 2023 Dec 10. Eur J Med Chem. 2024. PMID: 38096651
Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase.
Thoma G, Markert C, Lueoend R, Miltz W, Spanka C, Bollbuck B, Wolf RM, Srinivas H, Penno CA, Kiffe M, Gajewska M, Bednarczyk D, Wieczorek G, Evans A, Beerli C, Röhn TA. Thoma G, et al. Among authors: wieczorek g. J Med Chem. 2023 Dec 14;66(23):16410-16425. doi: 10.1021/acs.jmedchem.3c01866. Epub 2023 Nov 28. J Med Chem. 2023. PMID: 38015154
European Society of Toxicologic Pathology (Pathology 2.0 Molecular Pathology Special Interest Group): Review of In Situ Hybridization Techniques for Drug Research and Development.
Monné Rodríguez JM, Frisk AL, Kreutzer R, Lemarchand T, Lezmi S, Saravanan C, Stierstorfer B, Thuilliez C, Vezzali E, Wieczorek G, Yun SW, Schaudien D. Monné Rodríguez JM, et al. Among authors: wieczorek g. Toxicol Pathol. 2023 Apr;51(3):92-111. doi: 10.1177/01926233231178282. Epub 2023 Jul 14. Toxicol Pathol. 2023. PMID: 37449403 Free PMC article. Review.
Non-invasive molecular profiling of skin lesions using tape-stripping.
Kränke T, Loibner M, Arzberger E, Wieczorek G, Krenz T, Attig H, Hofmann-Wellenhof E, Fischer B, Eberhard A, Oberauner-Wappis L, Ulz CM, Fried I, Cerroni L, Oelmueller U, Zatloukal K, Hofmann-Wellenhof R, Heitzer E. Kränke T, et al. Among authors: wieczorek g. Skin Res Technol. 2023 May;29(5):e13322. doi: 10.1111/srt.13322. Skin Res Technol. 2023. PMID: 37231928 Free PMC article. No abstract available.
Single-cell transcriptomic analysis of renal allograft rejection reveals insights into intragraft TCR clonality.
Shi T, Burg AR, Caldwell JT, Roskin KM, Castro-Rojas CM, Chukwuma PC, Gray GI, Foote SG, Alonso JA, Cuda CM, Allman DA, Rush JS, Regnier CH, Wieczorek G, Alloway RR, Shields AR, Baker BM, Woodle ES, Hildeman DA. Shi T, et al. Among authors: wieczorek g. J Clin Invest. 2023 Jul 17;133(14):e170191. doi: 10.1172/JCI170191. J Clin Invest. 2023. PMID: 37227784 Free PMC article.
Preclinical characterization of the Toll-like receptor 7/8 antagonist MHV370 for lupus therapy.
Hawtin S, André C, Collignon-Zipfel G, Appenzeller S, Bannert B, Baumgartner L, Beck D, Betschart C, Boulay T, Brunner HI, Ceci M, Deane J, Feifel R, Ferrero E, Kyburz D, Lafossas F, Loetscher P, Merz-Stoeckle C, Michellys P, Nuesslein-Hildesheim B, Raulf F, Rush JS, Ruzzante G, Stein T, Zaharevitz S, Wieczorek G, Siegel R, Gergely P, Shisha T, Junt T. Hawtin S, et al. Among authors: wieczorek g. Cell Rep Med. 2023 May 16;4(5):101036. doi: 10.1016/j.xcrm.2023.101036. Cell Rep Med. 2023. PMID: 37196635 Free PMC article.
Single cell transcriptomic analysis of renal allograft rejection reveals novel insights into intragraft TCR clonality.
Shi T, Burg AR, Caldwell JT, Roskin K, Castro-Rojas CM, Chukwuma PC, Gray GI, Foote SG, Alonso J, Cuda CM, Allman DA, Rush JS, Regnier CH, Wieczorek G, Alloway RR, Shields AR, Baker BM, Woodle ES, Hildeman DA. Shi T, et al. Among authors: wieczorek g. bioRxiv [Preprint]. 2023 Feb 13:2023.02.08.524808. doi: 10.1101/2023.02.08.524808. bioRxiv. 2023. PMID: 36798151 Free PMC article. Updated. Preprint.
76 results