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Mitochondria-targeted anti-oxidant AntiOxCIN4 improved liver steatosis in Western diet-fed mice by preventing lipid accumulation due to upregulation of fatty acid oxidation, quality control mechanism and antioxidant defense systems.
Amorim R, Simões ICM, Teixeira J, Cagide F, Potes Y, Soares P, Carvalho A, Tavares LC, Benfeito S, Pereira SP, Simões RF, Karkucinska-Wieckowska A, Viegas I, Szymanska S, Dąbrowski M, Janikiewicz J, Cunha-Oliveira T, Dobrzyń A, Jones JG, Borges F, Wieckowski MR, Oliveira PJ. Amorim R, et al. Among authors: wieckowski mr. Redox Biol. 2022 Sep;55:102400. doi: 10.1016/j.redox.2022.102400. Epub 2022 Jul 16. Redox Biol. 2022. PMID: 35863265 Free PMC article.
Oxidative stress-dependent p66Shc phosphorylation in skin fibroblasts of children with mitochondrial disorders.
Lebiedzinska M, Karkucinska-Wieckowska A, Giorgi C, Karczmarewicz E, Pronicka E, Pinton P, Duszynski J, Pronicki M, Wieckowski MR. Lebiedzinska M, et al. Among authors: wieckowski mr. Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):952-60. doi: 10.1016/j.bbabio.2010.03.005. Epub 2010 Mar 10. Biochim Biophys Acta. 2010. PMID: 20226758 Free article.
Mitochondrial tolerance to drugs and toxic agents in ageing and disease.
Suski J, Lebiedzinska M, Machado NG, Oliveira PJ, Pinton P, Duszynski J, Wieckowski MR. Suski J, et al. Among authors: wieckowski mr. Curr Drug Targets. 2011 Jun;12(6):827-49. doi: 10.2174/138945011795529029. Curr Drug Targets. 2011. PMID: 21269267 Review.
Increased reactive oxygen species (ROS) production and low catalase level in fibroblasts of a girl with MEGDEL association (Leigh syndrome, deafness, 3-methylglutaconic aciduria).
Karkucinska-Wieckowska A, Lebiedzinska M, Jurkiewicz E, Pajdowska M, Trubicka J, Szymanska-Debinska T, Suski J, Pinton P, Duszynski J, Pronicki M, Wieckowski MR, Pronicka E. Karkucinska-Wieckowska A, et al. Among authors: wieckowski mr. Folia Neuropathol. 2011;49(1):56-63. Folia Neuropathol. 2011. PMID: 21455844 Free article.
Regulation and protection of mitochondrial physiology by sirtuins.
Pereira CV, Lebiedzinska M, Wieckowski MR, Oliveira PJ. Pereira CV, et al. Among authors: wieckowski mr. Mitochondrion. 2012 Jan;12(1):66-76. doi: 10.1016/j.mito.2011.07.003. Epub 2011 Jul 20. Mitochondrion. 2012. PMID: 21787885 Review.
p66Shc aging protein in control of fibroblasts cell fate.
Suski JM, Karkucinska-Wieckowska A, Lebiedzinska M, Giorgi C, Szczepanowska J, Szabadkai G, Duszynski J, Pronicki M, Pinton P, Wieckowski MR. Suski JM, et al. Among authors: wieckowski mr. Int J Mol Sci. 2011;12(8):5373-89. doi: 10.3390/ijms12085373. Epub 2011 Aug 22. Int J Mol Sci. 2011. PMID: 21954365 Free PMC article. Review.
Cardiac mitochondrial dysfunction during hyperglycemia--the role of oxidative stress and p66Shc signaling.
Diogo CV, Suski JM, Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Pronicki M, Duszynski J, Pinton P, Portincasa P, Oliveira PJ, Wieckowski MR. Diogo CV, et al. Among authors: wieckowski mr. Int J Biochem Cell Biol. 2013 Jan;45(1):114-22. doi: 10.1016/j.biocel.2012.07.004. Epub 2012 Jul 7. Int J Biochem Cell Biol. 2013. PMID: 22776741 Review.
Disrupted ATP synthase activity and mitochondrial hyperpolarisation-dependent oxidative stress is associated with p66Shc phosphorylation in fibroblasts of NARP patients.
Lebiedzinska M, Karkucinska-Wieckowska A, Wojtala A, Suski JM, Szabadkai G, Wilczynski G, Wlodarczyk J, Diogo CV, Oliveira PJ, Tauber J, Ježek P, Pronicki M, Duszynski J, Pinton P, Wieckowski MR. Lebiedzinska M, et al. Among authors: wieckowski mr. Int J Biochem Cell Biol. 2013 Jan;45(1):141-50. doi: 10.1016/j.biocel.2012.07.020. Epub 2012 Jul 31. Int J Biochem Cell Biol. 2013. PMID: 22885148
Left ventricular noncompaction (LVNC) and low mitochondrial membrane potential are specific for Barth syndrome.
Karkucinska-Wieckowska A, Trubicka J, Werner B, Kokoszynska K, Pajdowska M, Pronicki M, Czarnowska E, Lebiedzinska M, Sykut-Cegielska J, Ziolkowska L, Jaron W, Dobrzanska A, Ciara E, Wieckowski MR, Pronicka E. Karkucinska-Wieckowska A, et al. Among authors: wieckowski mr. J Inherit Metab Dis. 2013 Nov;36(6):929-37. doi: 10.1007/s10545-013-9584-4. Epub 2013 Jan 30. J Inherit Metab Dis. 2013. PMID: 23361305 Free PMC article.
Mitochondrial disruption occurs downstream from β-adrenergic overactivation by isoproterenol in differentiated, but not undifferentiated H9c2 cardiomyoblasts: differential activation of stress and survival pathways.
Branco AF, Sampaio SF, Wieckowski MR, Sardão VA, Oliveira PJ. Branco AF, et al. Among authors: wieckowski mr. Int J Biochem Cell Biol. 2013 Nov;45(11):2379-91. doi: 10.1016/j.biocel.2013.08.006. Epub 2013 Aug 16. Int J Biochem Cell Biol. 2013. PMID: 23958426
165 results