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Sensitive and Specific Detection of Low-Level Antibody Responses in Mild Middle East Respiratory Syndrome Coronavirus Infections.
Okba NMA, Raj VS, Widjaja I, GeurtsvanKessel CH, de Bruin E, Chandler FD, Park WB, Kim NJ, Farag EABA, Al-Hajri M, Bosch BJ, Oh MD, Koopmans MPG, Reusken CBEM, Haagmans BL. Okba NMA, et al. Among authors: widjaja i. Emerg Infect Dis. 2019 Oct;25(10):1868-1877. doi: 10.3201/eid2510.190051. Epub 2019 Oct 17. Emerg Infect Dis. 2019. PMID: 31423970 Free PMC article.
Serologic Detection of Middle East Respiratory Syndrome Coronavirus Functional Antibodies.
Okba NMA, Widjaja I, Li W, GeurtsvanKessel CH, Farag EABA, Al-Hajri M, Park WB, Oh MD, Reusken CBEM, Koopmans MPG, Bosch BJ, Haagmans BL. Okba NMA, et al. Among authors: widjaja i. Emerg Infect Dis. 2020 May;26(5):1024-1027. doi: 10.3201/eid2605.190921. Epub 2020 May 17. Emerg Infect Dis. 2020. PMID: 32150528 Free PMC article.
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.
Li W, Hulswit RJG, Widjaja I, Raj VS, McBride R, Peng W, Widagdo W, Tortorici MA, van Dieren B, Lang Y, van Lent JWM, Paulson JC, de Haan CAM, de Groot RJ, van Kuppeveld FJM, Haagmans BL, Bosch BJ. Li W, et al. Among authors: widjaja i. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):E8508-E8517. doi: 10.1073/pnas.1712592114. Epub 2017 Sep 18. Proc Natl Acad Sci U S A. 2017. PMID: 28923942 Free PMC article.
Towards a solution to MERS: protective human monoclonal antibodies targeting different domains and functions of the MERS-coronavirus spike glycoprotein.
Widjaja I, Wang C, van Haperen R, Gutiérrez-Álvarez J, van Dieren B, Okba NMA, Raj VS, Li W, Fernandez-Delgado R, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ. Widjaja I, et al. Emerg Microbes Infect. 2019;8(1):516-530. doi: 10.1080/22221751.2019.1597644. Emerg Microbes Infect. 2019. PMID: 30938227 Free PMC article.
Particulate multivalent presentation of the receptor binding domain induces protective immune responses against MERS-CoV.
Okba NMA, Widjaja I, van Dieren B, Aebischer A, van Amerongen G, de Waal L, Stittelaar KJ, Schipper D, Martina B, van den Brand JMA, Beer M, Bosch BJ, Haagmans BL. Okba NMA, et al. Among authors: widjaja i. Emerg Microbes Infect. 2020 Dec;9(1):1080-1091. doi: 10.1080/22221751.2020.1760735. Emerg Microbes Infect. 2020. PMID: 32471334 Free PMC article.
Chimeric camel/human heavy-chain antibodies protect against MERS-CoV infection.
Stalin Raj V, Okba NMA, Gutierrez-Alvarez J, Drabek D, van Dieren B, Widagdo W, Lamers MM, Widjaja I, Fernandez-Delgado R, Sola I, Bensaid A, Koopmans MP, Segalés J, Osterhaus ADME, Bosch BJ, Enjuanes L, Haagmans BL. Stalin Raj V, et al. Among authors: widjaja i. Sci Adv. 2018 Aug 8;4(8):eaas9667. doi: 10.1126/sciadv.aas9667. eCollection 2018 Aug. Sci Adv. 2018. PMID: 30101189 Free PMC article.
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies.
Wang C, van Haperen R, Gutiérrez-Álvarez J, Li W, Okba NMA, Albulescu I, Widjaja I, van Dieren B, Fernandez-Delgado R, Sola I, Hurdiss DL, Daramola O, Grosveld F, van Kuppeveld FJM, Haagmans BL, Enjuanes L, Drabek D, Bosch BJ. Wang C, et al. Among authors: widjaja i. Nat Commun. 2021 Mar 17;12(1):1715. doi: 10.1038/s41467-021-21968-w. Nat Commun. 2021. PMID: 33731724 Free PMC article.
In silico structure-based design and synthesis of novel anti-RSV compounds.
Cancellieri M, Bassetto M, Widjaja I, van Kuppeveld F, de Haan CA, Brancale A. Cancellieri M, et al. Among authors: widjaja i. Antiviral Res. 2015 Oct;122:46-50. doi: 10.1016/j.antiviral.2015.08.003. Epub 2015 Aug 8. Antiviral Res. 2015. PMID: 26259810 Free article.
22 results