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Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors.
ACS Med Chem Lett. 2016 Dec 27;8(2):239-244. doi: 10.1021/acsmedchemlett.6b00464. eCollection 2017 Feb 9.
ACS Med Chem Lett. 2016.
PMID: 28197319
Free PMC article.
Correction to "Structure Based Design of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors".
Johannes JW, Bates S, Beigie C, Belmonte MA, Breen J, Cao S, Centrella PA, Clark MA, Cuozzo JW, Dumelin CE, Ferguson AD, Habeshian S, Hargreaves D, Joubran C, Kazmirski S, Keefe AD, Lamb ML, Lan H, Li Y, Ma H, Mlynarski S, Packer MJ, Rawlins PB, Robbins DW, Shen H, Sigel EA, Soutter HH, Su N, Troast DM, Wang H, Wickson KF, Wu C, Zhang Y, Zhao Q, Zheng X, Hird AW.
Johannes JW, et al. Among authors: wickson kf.
ACS Med Chem Lett. 2017 Oct 18;8(11):1204. doi: 10.1021/acsmedchemlett.7b00397. eCollection 2017 Nov 9.
ACS Med Chem Lett. 2017.
PMID: 29152055
Free PMC article.
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Antibody fragments structurally enable a drug-discovery campaign on the cancer target Mcl-1.
Luptak J, Bista M, Fisher D, Flavell L, Gao N, Wickson K, Kazmirski SL, Howard T, Rawlins PB, Hargreaves D.
Luptak J, et al.
Acta Crystallogr D Struct Biol. 2019 Nov 1;75(Pt 11):1003-1014. doi: 10.1107/S2059798319014116. Epub 2019 Oct 31.
Acta Crystallogr D Struct Biol. 2019.
PMID: 31692474
Free PMC article.
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Rapid generation of a high quality lead for transforming growth factor-beta (TGF-beta) type I receptor (ALK5).
Goldberg FW, Ward RA, Powell SJ, Debreczeni JE, Norman RA, Roberts NJ, Dishington AP, Gingell HJ, Wickson KF, Roberts AL.
Goldberg FW, et al. Among authors: wickson kf.
J Med Chem. 2009 Dec 10;52(23):7901-5. doi: 10.1021/jm900807w.
J Med Chem. 2009.
PMID: 19736928
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Structure and characterization of a high affinity C5a monoclonal antibody that blocks binding to C5aR1 and C5aR2 receptors.
Colley CS, Popovic B, Sridharan S, Debreczeni JE, Hargeaves D, Fung M, An LL, Edwards B, Arnold J, England E, Eghobamien L, Sivars U, Flavell L, Renshaw J, Wickson K, Warrener P, Zha J, Bonnell J, Woods R, Wilkinson T, Dobson C, Vaughan TJ.
Colley CS, et al.
MAbs. 2018 Jan;10(1):104-117. doi: 10.1080/19420862.2017.1384892. Epub 2017 Oct 24.
MAbs. 2018.
PMID: 28952876
Free PMC article.
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Blocking phospholamban with VHH intrabodies enhances contractility and relaxation in heart failure.
De Genst E, Foo KS, Xiao Y, Rohner E, de Vries E, Sohlmér J, Witman N, Hidalgo A, Kolstad TRS, Louch WE, Pehrsson S, Park A, Ikeda Y, Li X, Mayr LM, Wickson K, Jennbacken K, Hansson K, Fritsche-Danielson R, Hunt J, Chien KR.
De Genst E, et al.
Nat Commun. 2022 May 31;13(1):3018. doi: 10.1038/s41467-022-29703-9.
Nat Commun. 2022.
PMID: 35641497
Free PMC article.
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Exploration of the HIF-1α/p300 interface using peptide and Adhiron phage display technologies.
Kyle HF, Wickson KF, Stott J, Burslem GM, Breeze AL, Tiede C, Tomlinson DC, Warriner SL, Nelson A, Wilson AJ, Edwards TA.
Kyle HF, et al. Among authors: wickson kf.
Mol Biosyst. 2015 Oct;11(10):2738-49. doi: 10.1039/c5mb00284b.
Mol Biosyst. 2015.
PMID: 26135796
Free article.
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