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G-CSF drives autoinflammation in APLAID.
Mulazzani E, Kong K, Aróstegui JI, Ng AP, Ranathunga N, Abeysekera W, Garnham AL, Ng SL, Baker PJ, Jackson JT, Lich JD, Hibbs ML, Wicks IP, Louis C, Masters SL. Mulazzani E, et al. Among authors: wicks ip. Nat Immunol. 2023 May;24(5):814-826. doi: 10.1038/s41590-023-01473-6. Epub 2023 Mar 30. Nat Immunol. 2023. PMID: 36997670 Free PMC article.
RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE. Lawlor KE, et al. Among authors: wicks ip. Nat Commun. 2015 Feb 18;6:6282. doi: 10.1038/ncomms7282. Nat Commun. 2015. PMID: 25693118 Free PMC article.
Targeting GM-CSF in inflammatory diseases.
Wicks IP, Roberts AW. Wicks IP, et al. Nat Rev Rheumatol. 2016 Jan;12(1):37-48. doi: 10.1038/nrrheum.2015.161. Epub 2015 Dec 3. Nat Rev Rheumatol. 2016. PMID: 26633290 Review.
A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean Fever.
Moghaddas F, Llamas R, De Nardo D, Martinez-Banaclocha H, Martinez-Garcia JJ, Mesa-Del-Castillo P, Baker PJ, Gargallo V, Mensa-Vilaro A, Canna S, Wicks IP, Pelegrin P, Arostegui JI, Masters SL. Moghaddas F, et al. Among authors: wicks ip. Ann Rheum Dis. 2017 Dec;76(12):2085-2094. doi: 10.1136/annrheumdis-2017-211473. Epub 2017 Aug 23. Ann Rheum Dis. 2017. PMID: 28835462 Free PMC article.
SIDT2 Transports Extracellular dsRNA into the Cytoplasm for Innate Immune Recognition.
Nguyen TA, Smith BRC, Tate MD, Belz GT, Barrios MH, Elgass KD, Weisman AS, Baker PJ, Preston SP, Whitehead L, Garnham A, Lundie RJ, Smyth GK, Pellegrini M, O'Keeffe M, Wicks IP, Masters SL, Hunter CP, Pang KC. Nguyen TA, et al. Among authors: wicks ip. Immunity. 2017 Sep 19;47(3):498-509.e6. doi: 10.1016/j.immuni.2017.08.007. Epub 2017 Sep 12. Immunity. 2017. PMID: 28916264 Free PMC article.
Autoinflammatory mutation in NLRC4 reveals a leucine-rich repeat (LRR)-LRR oligomerization interface.
Moghaddas F, Zeng P, Zhang Y, Schützle H, Brenner S, Hofmann SR, Berner R, Zhao Y, Lu B, Chen X, Zhang L, Cheng S, Winkler S, Lehmberg K, Canna SW, Czabotar PE, Wicks IP, De Nardo D, Hedrich CM, Zeng H, Masters SL. Moghaddas F, et al. Among authors: wicks ip. J Allergy Clin Immunol. 2018 Dec;142(6):1956-1967.e6. doi: 10.1016/j.jaci.2018.04.033. Epub 2018 May 17. J Allergy Clin Immunol. 2018. PMID: 29778503 Free PMC article.
162 results