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RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence of MLKL.
Lawlor KE, Khan N, Mildenhall A, Gerlic M, Croker BA, D'Cruz AA, Hall C, Kaur Spall S, Anderton H, Masters SL, Rashidi M, Wicks IP, Alexander WS, Mitsuuchi Y, Benetatos CA, Condon SM, Wong WW, Silke J, Vaux DL, Vince JE. Lawlor KE, et al. Among authors: wicks ip. Nat Commun. 2015 Feb 18;6:6282. doi: 10.1038/ncomms7282. Nat Commun. 2015. PMID: 25693118 Free PMC article.
Targeting GM-CSF in inflammatory diseases.
Wicks IP, Roberts AW. Wicks IP, et al. Nat Rev Rheumatol. 2016 Jan;12(1):37-48. doi: 10.1038/nrrheum.2015.161. Epub 2015 Dec 3. Nat Rev Rheumatol. 2016. PMID: 26633290 Review.
NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS.
Louis C, Souza-Fonseca-Guimaraes F, Yang Y, D'Silva D, Kratina T, Dagley L, Hediyeh-Zadeh S, Rautela J, Masters SL, Davis MJ, Babon JJ, Ciric B, Vivier E, Alexander WS, Huntington ND, Wicks IP. Louis C, et al. Among authors: wicks ip. J Exp Med. 2020 May 4;217(5):e20191421. doi: 10.1084/jem.20191421. J Exp Med. 2020. PMID: 32097462 Free PMC article.
TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells.
Balka KR, Louis C, Saunders TL, Smith AM, Calleja DJ, D'Silva DB, Moghaddas F, Tailler M, Lawlor KE, Zhan Y, Burns CJ, Wicks IP, Miner JJ, Kile BT, Masters SL, De Nardo D. Balka KR, et al. Among authors: wicks ip. Cell Rep. 2020 Apr 7;31(1):107492. doi: 10.1016/j.celrep.2020.03.056. Cell Rep. 2020. PMID: 32268090 Free article.
Inhibition of interleukin-1β signalling promotes atherosclerotic lesion remodelling in mice with inflammatory arthritis.
Dragoljevic D, Lee MKS, Louis C, Shihata W, Kraakman MJ, Hansen J, Masters SL, Hanaoka BY, Nagareddy PR, Lancaster GI, Wicks IP, Murphy AJ. Dragoljevic D, et al. Among authors: wicks ip. Clin Transl Immunology. 2020 Nov 9;9(11):e1206. doi: 10.1002/cti2.1206. eCollection 2020. Clin Transl Immunology. 2020. PMID: 33204425 Free PMC article.
172 results