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Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer.
Everest-Dass A, Nersisyan S, Maar H, Novosad V, Schröder-Schwarz J, Freytag V, Stuke JL, Beine MC, Schiecke A, Haider MT, Kriegs M, Elakad O, Bohnenberger H, Conradi LC, Raygorodskaya M, Krause L, von Itzstein M, Tonevitsky A, Schumacher U, Maltseva D, Wicklein D, Lange T. Everest-Dass A, et al. Among authors: wicklein d. Mol Oncol. 2024 Jan;18(1):62-90. doi: 10.1002/1878-0261.13535. Epub 2023 Nov 3. Mol Oncol. 2024. PMID: 37849446 Free PMC article.
Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy.
Ernst AK, Putscher A, Samatov TR, Suling A, Galatenko VV, Shkurnikov MY, Knyazev EN, Tonevitsky AG, Haalck T, Lange T, Maar H, Schröder-Schwarz J, Riecken K, Schumacher U, Wicklein D. Ernst AK, et al. Among authors: wicklein d. PLoS One. 2018 Feb 12;13(2):e0192525. doi: 10.1371/journal.pone.0192525. eCollection 2018. PLoS One. 2018. PMID: 29432466 Free PMC article.
Low expression of CD24 is associated with poor survival in colorectal cancer.
Nersisyan S, Ahlers AK, Lange T, Wicklein D, Galatenko A, Bohnenberger H, Elakad O, Conradi LC, Genduso S, Maar H, Schiecke A, Maltseva D, Raygorodskaya M, Makarova J, Schumacher U, Tonevitsky A. Nersisyan S, et al. Among authors: wicklein d. Biochimie. 2022 Jan;192:91-101. doi: 10.1016/j.biochi.2021.10.004. Epub 2021 Oct 9. Biochimie. 2022. PMID: 34637894
Fra-2 overexpression upregulates pro-metastatic cell-adhesion molecules, promotes pulmonary metastasis, and reduces survival in a spontaneous xenograft model of human breast cancer.
Arnold S, Kortland J, Maltseva DV, Nersisyan SA, Samatov TR, Lezius S, Tonevitsky AG, Milde-Langosch K, Wicklein D, Schumacher U, Stürken C. Arnold S, et al. Among authors: wicklein d. J Cancer Res Clin Oncol. 2022 Jun;148(6):1525-1542. doi: 10.1007/s00432-021-03812-2. Epub 2021 Oct 24. J Cancer Res Clin Oncol. 2022. PMID: 34693476 Free PMC article.
Tumor cell integrin β4 and tumor stroma E-/P-selectin cooperatively regulate tumor growth in vivo.
Genduso S, Freytag V, Schetler D, Kirchner L, Schiecke A, Maar H, Wicklein D, Gebauer F, Bröker K, Stürken C, Milde-Langosch K, Oliveira-Ferrer L, Ricklefs FL, Ewald F, Wolters-Eisfeld G, Riecken K, Unrau L, Krause L, Bohnenberger H, Offermann A, Perner S, Sebens S, Lamszus K, Diehl L, Linder S, Jücker M, Schumacher U, Lange T. Genduso S, et al. Among authors: wicklein d. J Hematol Oncol. 2023 Mar 17;16(1):23. doi: 10.1186/s13045-023-01413-9. J Hematol Oncol. 2023. PMID: 36932441 Free PMC article.
Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression.
Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, Tachezy M, Gebauer F, Lange T, Riecken K, Tonevitsky A, Aigner A, Izbicki J, Schumacher U, Wicklein D. Kemper M, et al. Among authors: wicklein d. J Exp Clin Cancer Res. 2021 Jun 26;40(1):214. doi: 10.1186/s13046-021-01946-2. J Exp Clin Cancer Res. 2021. PMID: 34174926 Free PMC article.
61 results