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Phase 1b/2a study of galunisertib, a small molecule inhibitor of transforming growth factor-beta receptor I, in combination with standard temozolomide-based radiochemotherapy in patients with newly diagnosed malignant glioma.
Wick A, Desjardins A, Suarez C, Forsyth P, Gueorguieva I, Burkholder T, Cleverly AL, Estrem ST, Wang S, Lahn MM, Guba SC, Capper D, Rodon J. Wick A, et al. Invest New Drugs. 2020 Oct;38(5):1570-1579. doi: 10.1007/s10637-020-00910-9. Epub 2020 Mar 5. Invest New Drugs. 2020. PMID: 32140889 Free PMC article. Clinical Trial.
Rechallenge with temozolomide in patients with recurrent gliomas.
Wick A, Pascher C, Wick W, Jauch T, Weller M, Bogdahn U, Hau P. Wick A, et al. Among authors: wick w. J Neurol. 2009 May;256(5):734-41. doi: 10.1007/s00415-009-5006-9. Epub 2009 Feb 25. J Neurol. 2009. PMID: 19240962 Free article.
Long-term analysis of the NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with PCV or temozolomide.
Wick W, Roth P, Hartmann C, Hau P, Nakamura M, Stockhammer F, Sabel MC, Wick A, Koeppen S, Ketter R, Vajkoczy P, Eyupoglu I, Kalff R, Pietsch T, Happold C, Galldiks N, Schmidt-Graf F, Bamberg M, Reifenberger G, Platten M, von Deimling A, Meisner C, Wiestler B, Weller M; Neurooncology Working Group (NOA) of the German Cancer Society. Wick W, et al. Among authors: wick a. Neuro Oncol. 2016 Nov;18(11):1529-1537. doi: 10.1093/neuonc/now133. Epub 2016 Jul 1. Neuro Oncol. 2016. PMID: 27370396 Free PMC article. Clinical Trial.
Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features.
Kickingereder P, Bonekamp D, Nowosielski M, Kratz A, Sill M, Burth S, Wick A, Eidel O, Schlemmer HP, Radbruch A, Debus J, Herold-Mende C, Unterberg A, Jones D, Pfister S, Wick W, von Deimling A, Bendszus M, Capper D. Kickingereder P, et al. Among authors: wick w, wick a. Radiology. 2016 Dec;281(3):907-918. doi: 10.1148/radiol.2016161382. Epub 2016 Sep 16. Radiology. 2016. PMID: 27636026
Radiomic subtyping improves disease stratification beyond key molecular, clinical, and standard imaging characteristics in patients with glioblastoma.
Kickingereder P, Neuberger U, Bonekamp D, Piechotta PL, Götz M, Wick A, Sill M, Kratz A, Shinohara RT, Jones DTW, Radbruch A, Muschelli J, Unterberg A, Debus J, Schlemmer HP, Herold-Mende C, Pfister S, von Deimling A, Wick W, Capper D, Maier-Hein KH, Bendszus M. Kickingereder P, et al. Among authors: wick w, wick a. Neuro Oncol. 2018 May 18;20(6):848-857. doi: 10.1093/neuonc/nox188. Neuro Oncol. 2018. PMID: 29036412 Free PMC article.
Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation-the NCT Neuro Master Match (N2M2) pilot study.
Pfaff E, Kessler T, Balasubramanian GP, Berberich A, Schrimpf D, Wick A, Debus J, Unterberg A, Bendszus M, Herold-Mende C, Capper D, Schenkel I, Eisenmenger A, Dettmer S, Brors B, Platten M, Pfister SM, von Deimling A, Jones DTW, Wick W, Sahm F. Pfaff E, et al. Among authors: wick w, wick a. Neuro Oncol. 2018 May 18;20(6):826-837. doi: 10.1093/neuonc/nox216. Neuro Oncol. 2018. PMID: 29165638 Free PMC article.
Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma.
Tejada Neyra MA, Neuberger U, Reinhardt A, Brugnara G, Bonekamp D, Sill M, Wick A, Jones DTW, Radbruch A, Unterberg A, Debus J, Heiland S, Schlemmer HP, Herold-Mende C, Pfister S, von Deimling A, Wick W, Capper D, Bendszus M, Kickingereder P. Tejada Neyra MA, et al. Among authors: wick w, wick a. Neuro Oncol. 2018 Oct 9;20(11):1517-1524. doi: 10.1093/neuonc/noy134. Neuro Oncol. 2018. PMID: 30107597 Free PMC article.
303 results