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Page 1
Mitochondrial DNA variants in obesity.
Knoll N, Jarick I, Volckmar AL, Klingenspor M, Illig T, Grallert H, Gieger C, Wichmann HE, Peters A, Wiegand S, Biebermann H, Fischer-Posovszky P, Wabitsch M, Völzke H, Nauck M, Teumer A, Rosskopf D, Rimmbach C, Schreiber S, Jacobs G, Lieb W, Franke A, Hebebrand J, Hinney A. Knoll N, et al. Among authors: wichmann he. PLoS One. 2014 May 2;9(5):e94882. doi: 10.1371/journal.pone.0094882. eCollection 2014. PLoS One. 2014. PMID: 24788344 Free PMC article.
Mutation screen in the GWAS derived obesity gene SH2B1 including functional analyses of detected variants.
Volckmar AL, Bolze F, Jarick I, Knoll N, Scherag A, Reinehr T, Illig T, Grallert H, Wichmann HE, Wiegand S, Biebermann H, Krude H, Fischer-Posovszky P, Rief W, Wabitsch M, Klingenspor M, Hebebrand J, Hinney A. Volckmar AL, et al. Among authors: wichmann he. BMC Med Genomics. 2012 Dec 27;5:65. doi: 10.1186/1755-8794-5-65. BMC Med Genomics. 2012. PMID: 23270367 Free PMC article.
Discovery of sexual dimorphisms in metabolic and genetic biomarkers.
Mittelstrass K, Ried JS, Yu Z, Krumsiek J, Gieger C, Prehn C, Roemisch-Margl W, Polonikov A, Peters A, Theis FJ, Meitinger T, Kronenberg F, Weidinger S, Wichmann HE, Suhre K, Wang-Sattler R, Adamski J, Illig T. Mittelstrass K, et al. Among authors: wichmann he. PLoS Genet. 2011 Aug;7(8):e1002215. doi: 10.1371/journal.pgen.1002215. Epub 2011 Aug 11. PLoS Genet. 2011. PMID: 21852955 Free PMC article.
Fat mass and obesity-associated gene (FTO) in eating disorders: evidence for association of the rs9939609 obesity risk allele with bulimia nervosa and anorexia nervosa.
Müller TD, Greene BH, Bellodi L, Cavallini MC, Cellini E, Di Bella D, Ehrlich S, Erzegovesi S, Estivill X, Fernández-Aranda F, Fichter M, Fleischhaker C, Scherag S, Gratacòs M, Grallert H, Herpertz-Dahlmann B, Herzog W, Illig T, Lehmkuhl U, Nacmias B, Ribasés M, Ricca V, Schäfer H, Scherag A, Sorbi S, Wichmann HE, Hebebrand J, Hinney A. Müller TD, et al. Among authors: wichmann he. Obes Facts. 2012;5(3):408-19. doi: 10.1159/000340057. Epub 2012 Jun 27. Obes Facts. 2012. PMID: 22797368 Free article.
A genome-wide association study confirms APOE as the major gene influencing survival in long-lived individuals.
Nebel A, Kleindorp R, Caliebe A, Nothnagel M, Blanché H, Junge O, Wittig M, Ellinghaus D, Flachsbart F, Wichmann HE, Meitinger T, Nikolaus S, Franke A, Krawczak M, Lathrop M, Schreiber S. Nebel A, et al. Among authors: wichmann he. Mech Ageing Dev. 2011 Jun-Jul;132(6-7):324-30. doi: 10.1016/j.mad.2011.06.008. Epub 2011 Jun 29. Mech Ageing Dev. 2011. PMID: 21740922 Clinical Trial.
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Kilpeläinen TO, Carli JF, Skowronski AA, Sun Q, Kriebel J, Feitosa MF, Hedman ÅK, Drong AW, Hayes JE, Zhao J, Pers TH, Schick U, Grarup N, Kutalik Z, Trompet S, Mangino M, Kristiansson K, Beekman M, Lyytikäinen LP, Eriksson J, Henneman P, Lahti J, Tanaka T, Luan J, Del Greco M F, Pasko D, Renström F, Willems SM, Mahajan A, Rose LM, Guo X, Liu Y, Kleber ME, Pérusse L, Gaunt T, Ahluwalia TS, Ju Sung Y, Ramos YF, Amin N, Amuzu A, Barroso I, Bellis C, Blangero J, Buckley BM, Böhringer S, I Chen YD, de Craen AJ, Crosslin DR, Dale CE, Dastani Z, Day FR, Deelen J, Delgado GE, Demirkan A, Finucane FM, Ford I, Garcia ME, Gieger C, Gustafsson S, Hallmans G, Hankinson SE, Havulinna AS, Herder C, Hernandez D, Hicks AA, Hunter DJ, Illig T, Ingelsson E, Ioan-Facsinay A, Jansson JO, Jenny NS, Jørgensen ME, Jørgensen T, Karlsson M, Koenig W, Kraft P, Kwekkeboom J, Laatikainen T, Ladwig KH, LeDuc CA, Lowe G, Lu Y, Marques-Vidal P, Meisinger C, Menni C, Morris AP, Myers RH, Männistö S, Nalls MA, Paternoster L, Peters A, Pradhan AD, Rankinen T, Rasmussen-Torvik LJ, Rathmann W, Rice TK, Brent Richards J, Ridker PM, Sattar N, Savage DB, Söderberg S, Timpson NJ, Vandenput L, van Heemst D, Uh HW, Vohl M… See abstract for full author list ➔ Kilpeläinen TO, et al. Among authors: wichmann he. Nat Commun. 2016 Feb 1;7:10494. doi: 10.1038/ncomms10494. Nat Commun. 2016. PMID: 26833098 Free PMC article.
A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease.
Wild PS, Zeller T, Schillert A, Szymczak S, Sinning CR, Deiseroth A, Schnabel RB, Lubos E, Keller T, Eleftheriadis MS, Bickel C, Rupprecht HJ, Wilde S, Rossmann H, Diemert P, Cupples LA, Perret C, Erdmann J, Stark K, Kleber ME, Epstein SE, Voight BF, Kuulasmaa K, Li M, Schäfer AS, Klopp N, Braund PS, Sager HB, Demissie S, Proust C, König IR, Wichmann HE, Reinhard W, Hoffmann MM, Virtamo J, Burnett MS, Siscovick D, Wiklund PG, Qu L, El Mokthari NE, Thompson JR, Peters A, Smith AV, Yon E, Baumert J, Hengstenberg C, März W, Amouyel P, Devaney J, Schwartz SM, Saarela O, Mehta NN, Rubin D, Silander K, Hall AS, Ferrieres J, Harris TB, Melander O, Kee F, Hakonarson H, Schrezenmeir J, Gudnason V, Elosua R, Arveiler D, Evans A, Rader DJ, Illig T, Schreiber S, Bis JC, Altshuler D, Kavousi M, Witteman JC, Uitterlinden AG, Hofman A, Folsom AR, Barbalic M, Boerwinkle E, Kathiresan S, Reilly MP, O'Donnell CJ, Samani NJ, Schunkert H, Cambien F, Lackner KJ, Tiret L, Salomaa V, Munzel T, Ziegler A, Blankenberg S. Wild PS, et al. Among authors: wichmann he. Circ Cardiovasc Genet. 2011 Aug 1;4(4):403-12. doi: 10.1161/CIRCGENETICS.110.958728. Epub 2011 May 23. Circ Cardiovasc Genet. 2011. PMID: 21606135 Free PMC article.
CONAN: copy number variation analysis software for genome-wide association studies.
Forer L, Schönherr S, Weissensteiner H, Haider F, Kluckner T, Gieger C, Wichmann HE, Specht G, Kronenberg F, Kloss-Brandstätter A. Forer L, et al. Among authors: wichmann he. BMC Bioinformatics. 2010 Jun 14;11:318. doi: 10.1186/1471-2105-11-318. BMC Bioinformatics. 2010. PMID: 20546565 Free PMC article.
Human serum metabolic profiles are age dependent.
Yu Z, Zhai G, Singmann P, He Y, Xu T, Prehn C, Römisch-Margl W, Lattka E, Gieger C, Soranzo N, Heinrich J, Standl M, Thiering E, Mittelstraß K, Wichmann HE, Peters A, Suhre K, Li Y, Adamski J, Spector TD, Illig T, Wang-Sattler R. Yu Z, et al. Among authors: he y, wichmann he. Aging Cell. 2012 Dec;11(6):960-7. doi: 10.1111/j.1474-9726.2012.00865.x. Epub 2012 Aug 27. Aging Cell. 2012. PMID: 22834969 Free PMC article.
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